High Capacity Freeze-dryer for Interdisciplinary and Interdepartmental Research

这笔赠款将用于购买一台大容量多用途冷冻干燥机，用于跨学科和跨部门研究。部门。多伦多大学密西索加分校(UTM)生物学和地理系拥有一支充满活力和生产力的教职员工和HQP团队，他们将将基因与生态系统联系起来的问题整合在一起，同时研究蓝藻、植物、真菌、昆虫和哺乳动物等各种生物。我们部门的许多研究计划要求长期保存生物样本，包括寡核苷酸、肽、蛋白质、次生代谢物、土壤、真菌细胞、动植物组织。冷冻干燥(或冷冻干燥)为这些样品提供了最好的长期保存，因为它通过升华在低温和压力下温和地干燥热敏感材料。根据这种设备的基本性质和迫切需要，两个部门的8名研究人员就这项提议进行了合作，该部还提供了额外的财政、后勤和技术支助。生物系和研究部副主任办公室。这些设备对于每个PIS实验室的HQP的成功培训和生产效率至关重要。我们预计，在冻干机20年的使用寿命内，该设备将为培训&GT；800 HQP做出贡献。

This grant will support the purchase of one high-capacity multi-purpose freeze-dryer for interdisciplinary and interdepartmental research. The Depts. of Biology and Geography at the University of Toronto Mississauga (UTM) have a vibrant and productive group of faculty and HQP who together integrate questions that link genes to ecosystems, while working on organisms as diverse as cyanobacteria, plants, fungi, insects and mammals. Many research programmes in our departments require the long-term preservation of biological samples that include oligonucleotides, peptides, proteins, secondary metabolites, soil, fungal cells, animal and plant tissues. Freeze-drying (or lyophilizing) provides the best long-term preservation of these samples because it gently dries thermally sensitive materials at low temperature and pressure by sublimation. Based on the essential nature and urgent need of this equipment, eight researchers across two departments have collaborated on this proposal, with additional financial, logistical and technical support offered by the Dept. of Biology and the Office of the Vice-Principal of Research. This equipment will be essential for the successful training and productivity of HQP in each of the PIs labs. We anticipate that over a 20 year lifespan of the freeze-dryer, this equipment will contribute to the training of >800 HQP.