Supercritical fluid extraction (SFE) process development of Thuja Occidentalis essential oil

西雪松，又名东方白柏，是加拿大东部的一种土生土长的树木。植物的叶子是第一个 16世纪加拿大印第安人用来治疗坏血病的一种药物。在……里面 传统医学，西方图贾牛皮癣，支气管炎，子宫癌和 风湿治疗。西葫芦挥发油具有治疗多囊等疗效 卵巢综合症，并具有驱虫和杀虫特性。 植物精油通常通过水蒸气蒸馏或溶剂萃取法分离。这些 这些技术存在挥发性物质损失、萃取效率低、运行时间长等缺点。 提取时间，不饱和化合物和有毒溶剂残留物的降解。强制使用 精油提取的替代技术。另一种替代方法是使用超临界流体萃取(SFE) 二氧化碳作为超临界流体，在低温下产生无溶剂提取物，从而避免了 活性化合物的降解。二氧化碳被广泛使用，因为它无毒，化学稳定， 在环境上可以接受，很容易从萃取物中分离出来，因为它在正常情况下是以气体形式存在的 大气条件。此外，与萃取物相比，超临界萃取物具有更好的品质 通过水蒸气蒸馏或用液体溶剂生产。 ANPI加拿大公司是一家专门从事森林提取物的公司，该公司希望开发一种超临界流体工艺， 二氧化碳从东方白柏中提取高质量的精油，没有碳足迹。

Thuja Occidentalis called also eastern white cedar is an eastern Canada native tree. The plant leaves were first identified as a remedy by native Indians in Canada during the 16th century for the treatment of scurvy. In traditional medicine, Thuja occidentalis work as a psoriasis, bronchial catarrh, uterine carcinomas and rheumatism treatment. Thuja occidentalis essential oil has curative properties such as treatment of polycystic ovary syndrome and has vermifuge and insecticidal properties. The essential oil of plants has been usually isolated by either hydrodistillation or solvent extraction. These techniques presents some drawbacks such as loss of volatile compounds, low extraction efficiency, long extraction time, degradation of unsaturated compound and toxic solvent residue. that make mandatory the use of alternative techniques for essential oil extraction. An alternative is supercritical fluid extraction (SFE) using CO2 as the supercritical fluid, which produces solvent-free extracts at low temperatures thus avoiding the degradation of active compound. CO2 is widely used because it is non toxic, chemically stable, environmentally acceptable and easily separate from the extract since it exists as a gas under normal atmospheric conditions. Furthermore, supercritical extracts have a superior quality by comparison with extracts produced by hydrodistillation or with liquid solvents. ANPI Canada, a company specialized in forest extracts, wants to develop a supercritical fluid process with CO2 to extract a high quality essential oil from eastern white cedar with no carbon footprint.