Characterisation of the novel mitochondrial protein (CABC1/ADCK3) and its role in protecting against oxidative stress

这是第一个详细的特征和机制研究的蛋白质，防止氧化应激和神经变性。证明这种氧化应激的基础及其对细胞表型的可能贡献将有助于理解疾病过程并最终设计最小化氧化应激的方法。对这种蛋白质的研究为研究者在该领域的前沿工作提供了一个机会，增加了澳大利亚在该领域的科学领导地位。它也代表了研究生培训的理想项目，是布里斯班和墨尔本团体之间的合作。

This is the first detailed characterisation and mechanistic study on a protein that protects against oxidative stress and neurodegeneration. Demonstrating the basis for this oxidative stress and its possible contribution to the cellular phenotype will be of benefit in understanding the disease process and ultimately designing approaches to minimise oxidative stress. An investigation of this protein presents an opportunity for the investigator to work at the forefront in this field adding to Australia's scientific leadership in the area. It also represents an ideal project for post-graduate training and is a collaboration between groups in Brisbane and Melbourne.