Pre-clinical evaluation of snake venom proteins with therapeutic potential
Pre-clinical evaluation of snake venom proteins with therapeutic potential
批准号:
LP0882340
负责人:
Prof Martin Lavin
金额:
$55.68万
依托单位国家:
澳大利亚
项目类别:
Linkage Projects
财政年份:
2008
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2008-01-10 至 2012-12-31
中文摘要
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英文摘要
Australia harbors some of the most toxic snakes in the world. Their venoms contain a range of substances that are designed to rapidly immobilize and kill their prey. These include agents that lead to enhanced blood clotting; excess bleeding. We have isolated and characterized a large number of the components involved over the last several years. The aim here is to carry out pre-clinical trials in animal models to test the efficacy of three proteins as anti-bleeding agents and investigate several other novel components. The ultimate outcome will be the development of novel drugs that will have application in the treatment of human disorders.
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