FASEB Summer Research Conference: Circumventricular Organs to be held Saxtons River, VT; July 17-22, 1993

大脑被一层相对不易渗透的血脑屏障保护着，血脑屏障是由环绕在大脑毛细血管周围的神经胶质细胞形成的。但这一屏障也存在漏洞。特殊分化的器官——脑室周围器官——在脑室壁上含有神经元和各种血源性化学物质的受体。这些神经元形成早期预警网络，维持大脑和身体的稳态。它们是自主神经和神经内分泌系统功能的重要调节因子。这些器官中的一些在血压调节中发挥着至关重要的作用，但目前还不清楚新发现的肽神经递质的作用，也不清楚这些器官是如何作为一个系统一起发挥作用的。这项NSF资助将允许8名年轻科学家参加由实验生物学联合会组织的关于心室周围器官的夏季研究会议。本次会议的目的是将基础和临床科学家聚集在一起交流信息，并促进对这一研究领域潜在重要性的更好理解。＊＊＊

Johnson Gross 9224876 The brain is protected from contact with the environment by a relatively impermeable blood-brain barrier induced by the neuroglial cells that surround brain capillaries. But there are gaps in this barrier. Specially differentiated organs -- circumventricular organs -- in the ventricular walls contain neurons with receptors for a variety of blood-borne chemicals. These neurons form early warning networks that maintains brain and body homeostasis. They are influential regulators of autonomic and neuroendocrine system functions. Some of these organs have shown to be crucially important in the regulation of blood pressure but there is as yet no understanding of the role of the newly discovered peptide neurotransmitters or how the organs function together as a system. This NSF grant will allow eight young scientists to participate in a summer research conference on the circumventricular organs organized by the Federated Societies of Experimental Biology. The purpose of this conference is to bring basic and clinical scientists together to exchange information and to foster a greater understanding of the potential importance of this area of research. ***