U.S.-Japan Cooperative Science: Experimental and Theoretical Studies on Stucture and Catalytic Activity of di- and Polynuclear Metal Complexes

9726789 Ojima该奖项支持由纽约州立大学石溪分校的Iwao Ojima教授、埃默里大学的Keiji Morokuma教授和日本东京大学的Eiichi Nakamura教授共同开展的为期三年的合作研究项目。研究人员将对双核和多核金属配合物的结构和催化活性进行实验和理论研究。Ojima教授一直致力于设计和开发由杂双金属催化剂体系促进的新型高效均相催化反应，为有机合成提供了有用的合成方法。他发现了硅基甲酰化和各种硅基碳环化，并一直试图阐明这些催化过程的最合理的机制。他与理论化学家合作，他们在分析均相催化和双核/多核金属络合系统的问题方面有经验，将为理论预测的途径提供见解。该项目汇集了三个具有互补专业知识、研究能力和设备的实验室的努力。Ojima教授的专长是有机金属化学和均相催化。Morokuma教授是一位理论化学家，他能独特地处理过渡金属催化过程的催化循环。中村教授在实验和理论研究方面拥有广泛的专业知识。预计这项三方合作研究将揭示双核和多核金属配合物催化的新机制，这很可能意味着催化循环中新的有机金属物种。这一信息将激发对新的和重要的有机金属转化的探索，并有助于设计高区域、立体和对映选择性催化剂体系，并在工业过程中应用。通过思想和技术的交流，该项目将扩大我们的基础知识基础，促进国际了解与合作。* * *

9726789 Ojima This award supports a three year collaborative research project between Professor Iwao Ojima of SUNY, Stony Brook, Professor Keiji Morokuma of Emory University and Professor Eiichi Nakamura of the University of Tokyo in Japan. The researchers will be undertaking experimental and theoretical studies on structure and catalytic activity of di- and polynuclear metal complexes. Professor Ojima has been designing and developing new and efficient homogeneous catalytic reactions promoted by heterobimetallic catalyst systems, that provide useful synthetic methods for organic synthesis. He has discovered silylformylation and various silylcarbocyclizations and has been trying to elucidate the most plausible mechanisms for these catalytic processes. His collaborations with theoretical chemists, who have experience in analyzing the problems in homogeneous catalysis and di-/polynuclear metal complex systems, will provide insight into the theoretically predicted pathways. This project brings together the efforts of three laboratories that have complementary expertise, research capabilities and equipment. Professor Ojima's expertise is in organometallic chemistry and homogeneous catalysis. Professor Morokuma is a theoretical chemist who can uniquely deal with the catalytic cycles of transition metal catalyzed processes. Professor Nakamura has a wide range of expertise in experimental as well as theoretical research. It is anticipated that this trilateral collaborative research will disclose novel mechanistic aspects of the catalysis of di- and polynuclear metal complexes, which are very likely to imply new organometallic species in the catalytic cycle. This information will stimulate the exploration of new and significant organometallic transformations and help in the design of highly regio-, stereo- and enantioselective catalyst systems with applications in industrial processes. Through the exchange of ideas and technology, this project will broaden o ur base of basic knowledge and promote international understanding and cooperation. ***