Gene regulatory networks in heart development

在人类中，心脏的结构和功能畸形非常常见，并与高经济和情感负担有关。在这个项目中，我们将研究遗传网络如何在分子水平上启动和控制心脏发育。我们将建立和使用最先进的技术和生物信息学工具来详细探索心脏调节基因的功能。我们的工作将有助于发现新的心脏途径，以便更好地了解心脏形成和疾病，并开发先进技术，有助于加强澳大利亚的基础和战略研究。

In humans, structural and functional malformations of the heart are very common and are associated with a high economic and emotional burden. In this project, we will study how genetic networks initiate and control heart development at a molecular level. We will establish and employ state-of-the-art technologies and bioinformatics tools to explore the function of cardiac regulatory genes in detail. Our work will contribute both to discover new cardiac pathways for a better understanding of heart formation and disease, and to develop advanced techniques that will contribute to strengthen Australian basic and strategic research.