Conference: 2007 CSHL Conference on Mechanisms of Eukaryotic Transcription being held in Cold Spring Harbor, NY on September 5-9, 2007.
Conference: 2007 CSHL Conference on Mechanisms of Eukaryotic Transcription being held in Cold Spring Harbor, NY on September 5-9, 2007.
批准号:
0721631
负责人:
Terri Grodzicker
金额:
$0.3万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2007
资助国家:
美国
项目状态:
已结题
起止时间:
2007-08-15 至 2008-07-31
中文摘要
在包括植物和动物在内的高等生物中,遗传密码(DNA)可以在被称为细胞核的细胞内部隔间找到,紧密地包装在DNA-蛋白质复合体中的染色体中,称为染色质。当信使RNA(MRNA)在称为转录的过程中从DNA密码中复制出来时,基因就会表达出来,然后离开细胞核,在称为核糖体的“蛋白质工厂”将其翻译成蛋白质。转录现在被认为是一个高度协调的过程,在生物体生命的不同阶段,一组基因的表达被开启和关闭。这次国际会议旨在成为讨论该领域最新研究的论坛,并促进我们对这一复杂而基本的生物过程的理解的未来进展。这次会议之所以值得注意,是因为大多数演讲都是从公开提交的摘要中挑选出来的,这为包括研究生在内的年轻科学家提供了广泛和多样化的代表来展示他们的最新研究成果的充分机会。国家科学基金会的资金将主要用于支持初级科学家和该领域中代表人数不足的成员,否则他们将无法出席。
英文摘要
In higher organisms including plants and animals, the genetic code (DNA) is to be found in an internal compartment of the cell known as the nucleus, tightly packaged into chromosomes in a DNA-protein complex called chromatin. Genes are expressed when messenger RNAs (mRNA) are copied off the DNA code in a process called transcription, before leaving the nucleus to be translated into proteins at "protein factories" called ribosomes. Transcription is now known to be a highly orchestrated process, with expression of sets of genes being turned on and off at various stages of the life of the organism. This international conference is intended to be a forum for discussion of the latest research in the field and to promote future progress in our understanding of this complex and fundamental biological process. This conference is notable because the majority of talks are selected from openly submitted abstracts giving ample opportunity for broad and diverse representation of junior scientists including graduate students to present their latest research. National Science Foundation funding will primarily be used to support junior scientists and members of under-represented constituencies within the field who would otherwise not be able to attend.
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