Acquisition of a quadrupole time-of-flight mass spectrometer

根据化学研究仪器和设施：部门多用户仪器计划（CRIF:MU）的这份合同，克里斯塔·l·科尔耶教授和丽贝卡·w·亚历山大教授将获得一台四极杆飞行时间（Q-TOF）质谱仪（MS）。该仪器将用于支持以下领域的研究：1)基于亲和的毛细管电泳研究，以促进生物探针设计和微生物检测；2)剖析甲硫基- trna合成酶的结构域间通讯；3)天然产物间激发态能量传递；4)亚硫酸还原的结构与氧化还原化学；5)通过整合基因组、蛋白质组学和代谢组学数据，对拟南芥的生物网络进行建模；6)半胱氨酸磺酸的催化和调控作用。质谱法（MS）是通过测量样品中分子组分电离后经质谱仪检测后的质量，来鉴定样品的化学成分并确定其纯度的方法。质谱法是化学家和生物化学家使用最广泛的分析工具之一。此次收购将通过系里和本科化学实验室的研究项目，为本科生和研究生提供使用现代仪器的技术培训。

With this award from the Chemistry Research Instrumentation and Facilities: Departmental Multi-User Instrumentation program (CRIF:MU), Professors Christa L. Colyer and Rebecca W. Alexander will acquire a quadrupole time-of-flight (Q-TOF) mass spectrometer (MS). The instrument will be used to support research in the following areas: 1) affinity-based capillary electrophoresis studies to facilitate bioprobe design and microbe detection; 2) dissecting inter-domain communication in methionyl-tRNA synthetase; 3) excited state energy transfer amongst natural products; 4) structures and redox chemistry in sulfinic acid reduction; 5) modeling biological networks in arabidopsis through integration of genomic, proteomic, and metabolomic data; and, 6) cysteine sulfenic acids in catalysis and regulation.Mass spectrometry (MS) is used to identify the chemical composition of a sample and determine its purity by measuring the mass of the molecular constituents in the sample after they are ionized and detected by the mass spectrometer. Mass spectrometry is one of the most widely used analytical tools by chemists and biochemists. The acquisition will provide training for undergraduate and graduate students in this technique using modern instrumentation through research programs in the department and in the undergraduate chemistry laboratories.