Biomechanics of Needle Insertion

插针是最常见的神经外科手术之一。然而，人们对这一过程的生物力学知之甚少。未知因素包括针头在载荷作用下的脑组织变形和针头穿透脑组织时的偏转。我们将开发针头插入的计算模型。它们将包括脑组织的非线性材料特性，大变形，以及包括摩擦在内的针-组织接触模型。这家日本集团将开发测试方法来验证数学模型。实验装置包括测量组织内变形和针头偏转的双轴X射线，以及测量针尖反作用力和针边摩擦力的传感器。

Needle insertion is one of the most common neurosurgical procedures. However, the biomechanics of this process is poorly understood. The unknown factors include brain tissue deformation under load imposed by the needle and needle deflection when penetrating brain tissue. We will develop computational models of needle insertion. They will include non-linear material properties of the brain tissue, large deformations, and needle-tissue contact model including friction. The Japanese group will develop testing methods to validate mathematical models. Experimental set-up includes bi-axial x-ray to measure deformation within the tissue and needle deflection, and a sensor measuring reaction force on needle tip and friction force on needle sides.