Console solid-state NMR 400 MHz

现有的400 MHz固态NMR光谱仪的拟议更换控制台，包括用于测量扩散系数的梯度系统的控制，是Martin-Luther-University Halle物理研究所NMR系的中心研究仪器。该仪器用于解决软凝聚物质的结构和动力学领域的研究问题，特别是在合成和生物聚合物系统以及脂质膜中。在合成聚合物领域，结构-动力学-性质关系使用NMR方法（1H时域NMR、弛豫法、宽线光谱、多维NMR、高分辨率固态NMR、扩散法）的组合进行探索，而固态蛋白质主要是高分辨率和多维方法的领域。正在进行的合成聚合物领域的项目涉及拉伸聚合物玻璃中的取向有序、不同类型聚合物网络和凝胶中的网络网状结构和传输现象、聚合物纳米复合材料中的动力学以及半结晶聚合物中的结构形成和动力学。在生物大分子领域，重点是瞬时组装蛋白质（包括来自眼睛透镜的蛋白质）中的旋转和平移扩散以及固态蛋白质的全局摇摆运动。在脂质膜中，分子动力学具有高精度的特点，并与计算机模拟相匹配;此外，它们还可以作为聚合物结晶的限制几何形状。计划中的未来项目将研究液-液相分离后的全球蛋白质动力学，蛋白质动力学和固态包装耦合工作的扩展，填充弹性体共混物的微观结构和老化行为的阐明，缔合聚合物的松弛机制，新聚酯和玻璃化聚合物的动力学和结晶，以及更复杂生物膜系统的动力学。

The proposed replacement console for an existing 400 MHz solid-state NMR spectrometer including controls for a gradient system for the measurement of diffusion coefficients is the central research instrument of the NMR department at the Institute of Physics of the Martin-Luther-University Halle. The instrument is used to address research questions in the area of structure and dynamics in soft condensed matter, especially in synthetic and biological polymer systems as well as in lipid membranes. In the area of synthetic polymers, structure-dynamics-property relations are explored using a combination of NMR methods (1H time-domain NMR, relaxometry, broad-line spectroscopy, multidimensional NMR, high-resolution solid-state NMR, diffusometry), while proteins in the solid state are primarily the domain of high-resolution and multidimensional methods. Ongoing projects in the field of synthetic polymers deal with orientational ordering in stretched polymer glasses, network mesh structure and transport phenomenon in different types of polymer networks and gels, dynamics in polymer nanocomposites, and structure formation and dynamics in semi-crystalline polymers. In the field of biological macromolecules, the focus is on rotational and translational diffusion in transiently assembling proteins (including those from the eye lens) and global rocking motions of proteins in the solid state. In lipid membranes, molecular dynamics are characterized with high accuracy and matched with computer simulations; furthermore, they serve as confining geometry for polymer crystallization. Planned future projects will pursue global protein dynamics upon liquid-liquid phase separation, an extension of work on the coupling of protein dynamics and packing in the solid state, elucidation of the microstructure and aging behavior of filled elastomer blends, relaxation mechanisms in associating polymers, the dynamics and crystallization of new polyesters and vitrimers, and dynamics in more complex biological membrane systems.