influence of the characteristics of light transmission through the lens on the visual function of cataractou eyes
influence of the characteristics of light transmission through the lens on the visual function of cataractou eyes
批准号:
07671939
负责人:
SASAKI Kazuyuki
金额:
$1.47万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
1995
资助国家:
日本
项目状态:
已结题
起止时间:
1995 至 1996
中文摘要
为了模拟白内障晶状体混浊后在视网膜上反射的影像,本文研究了白内障模型的影像质量与混浊程度及混浊类型的关系。第一年进行了以下研究:1)用离体人核性白内障晶状体和大鼠晶状体材料阐明了光谱透射因子(T%)与光散射强度(SI)的相关性。2)核性白内障透镜的光学玻璃模型是通过将乳胶颗粒悬浮液注入中央腔而产生的。通过T%和SI来量化模型镜片的浑浊度等级,通过调制传递函数(MTF)来评价模型镜片的分辨率。3)使用带有35 mm胶片的钢照相机,评价通过模型透镜拍摄的图像的质量和细节。通过核白内障透镜获得的图像对应于 ...更多信息 超过日本白内障流行病学协作组系统的II级,显示对比度和亮度降低。研究的第二年:1)研制了一种新型的核和囊下白内障模型透镜。1-1.为了更接近地模拟人类透镜条件,核性白内障模型由聚甲基丙烯酸甲酯(PMMA)制成,切割波长低于390 nm(UV)。核性白内障模型的形状为双凸面人工晶状体类型,并且通过亲水性和疏液性单体的聚合来制造混浊。1-ii.通过该模式的图像是通过钢照相机获得的。对比度的下降通过切割紫外线而减少,使人类形象通过多达60%的透射透镜被识别为主体。1-iii.将由紫外线切割人工晶状体和硬接触透镜(HCL)组成的囊下混浊模型透镜贴附在人工晶状体后,在晶状体之间的差距中植入白色微粒。2)研制了一种新型的图像模拟摄像机。新相机的特点是:一个模型透镜,这是在水中举行和CCD相机,这是用作摄影介质。反射图像的真实的实时观察和图像输入计算机是容易的。用新的照相机检查具有囊下混浊的模型透镜。为了评价通过模型镜片的图像,使用了视力表、点光源、分辨率表和人体图。3)通过具有囊下混浊的模型获得的图像在混浊中心处的130 cct SI下没有显示图像对比度或亮度的任何降低,即使当不透明区域被放大时。4)通过后囊下白内障的一个特定的情况下,进行了模拟的图像。本研究能够成功地获得通过两种类型的透镜乳浊的图像质量的特性。少
英文摘要
In order to simulate on image which is reflected on the retina through opacified lenses, the relationship between the quality of images through model catarctous and the grading of their opacification or opacification types was investigated. In the first year the following studies were performed : 1) Correlation between spectral transmisson factor (T%) and light scattering intensity (SI) in vivo was clarified by (or through) materials of extracted human nuclear cataract lenses and rat lenses. 2) The optical glass model of a lens with nuclear cataract was produced by a suspension of latex particles injected into the central cavity. The opacification grade of the model lenses was quantified by their T% and SI.The resolution of the lenses was evaluated by their modulation transfer function (MTF). 3) Using a steel camera with 35mm film, the quality and detail of photographed images through the model lenses were evaluated. The images obtained through the nuclear catarctous lens corresponded … More with over grade II of the Japanese Cataract Cooperative Epidemiology Study Group system, showing a decrease of contrast and brightness. In the second year of the study : 1) A new type of nuclear and subcapsular cataract model lens was developed. 1-1. To closely simulate human lens conditions, the nuclear cataract model was made of poly-methyl-methacrylate (PMMA) with a cutting wavelength below 390nm (UV). The shape of the nuclear cataract model was the biconvex IOL type and the opacification was made by the polymerization of both hydrophile and lyophobic monomers. 1-ii. Images through this mode were obtained through a steel camera. The decrease in contrast was diminished by cutting UV,making human figures recognizable as subjects through as much as 60% of the transmission lens. 1-iii. The model lens of subcapsular opacification composed of UV-cut IOL and hard contact lens (HCL) was attached behind IOL and whitish corpuscles were inserted in the gap between the lenses. 2) A new type of camera for image simulation was developed. The characteristics of the new camera are ; a model lens which is held in water and a CCD camera that is used as a photographic medium. Real time observation of the reflected images and image input into the computer were easily possible. The model lens with subcapsular opacity was examined by the new camera. To evaluate images through the model lenses, a visual acuity chart, point light source, resolution chart and human figure were used. 3) Images obtained through the model with subcapsular opacity did not show any decrease in image contrast or brightness under 130 cct of SI at the center of the opacity even when the opaque area was enlarged. 4) The simulation of an image was performed through a posterior subcapsular cataract for a particular case. The study was able to successfully obtain the characteristics of image quality through two types of lens opacification. Less
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Kuruto Fujisawa, Kazuyuki Sasaki: "Changes in Light Scattering Intensity of the Transparent Lenses of Subjects Selected from Population-Based Surveys Depending on Age ; Analysis through Scheimpflug Images." Ophthalmic Research. 27. 89-101 (1995)
Kuruto Fujisawa、Kazuyuki Sasaki:“从基于人口的调查中选择的受试者的透明镜片的光散射强度随年龄的变化;通过 Scheimpflug 图像进行分析。”
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H.Sasaki: "Aging Changes of Lens Transparency in Subjects with Noncataractous Eyes" Developments in Ophthalmology. 27. 102-108 (1997)
H.Sasaki:“非白内障眼睛受试者晶状体透明度的老化变化”眼科进展。
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Keinosuke Nishimoto, Kazuyuki Sasaki: "In vivo Linght Scattering Intensity in the Lens versus in vitro Spectral Transmission in the Nuclear Region" Ophthaimic Research. 27. 1-11 (1995)
Keinosuke Nishimoto、Kazuyuki Sasaki:“晶状体中的体内光散射强度与核区域的体外光谱传输”眼科研究。
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坂本保夫: "混濁水晶体・偽水晶体眼の網膜投影像評価法" 金沢医科大学雑誌. 21. 508-511 (1996)
Yasuo Sakamoto:“浑浊和人工晶状体眼的视网膜投影评估方法”金泽医科大学学报21. 508-511(1996)。
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坂本保夫: "混濁水晶体・偽水晶体眼の網膜投影像評価法" 金沢医科大学雑誌. 21. 508-511 (1997)
Yasuo Sakamoto:“浑浊和人工晶状体眼的视网膜投影评估方法”金泽医科大学学报,21. 508-511(1997)。
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共 18 条
The relation of ultraviolet B exposure development cataract and acceleration of the progression of cataract opacification of atopic cataract expression mechanism.
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批准号:09671821
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.66万
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财政年份:1997
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负责人:SASAKI Kazuyuki
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依托单位:
Studies on Progression of Cataract Observed After Vitreous Surgery
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批准号:02670798
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1990
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负责人:SASAKI Kazuyuki
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依托单位:
海外基金