Development on evaluation method of thought and personality disorders based on quantitative individuality of language behavior and brain functional information

基于脑活动数据、心理测试结果、对话中的行为模式、受试者对心理状态的认知印象等四种与人格相关的数据，对思维和人格障碍的客观评价方法以及包括社交技能训练在内的治疗方法的发展进行了调查，得到了以下结果。我们分析了神经调节剂的血液代谢数据作为个体的候选者的大脑代谢数据。提取与语言和思维过程相关的多通道脑电和脑磁图的个性特征。我们在治疗中测量了思维和人格障碍患者的诊断行为。皮质-皮质下系统的MR图像表现出一定的个性化和异常性。我们将心理测试和心理测试改进为计算机控制的测试系统，同时测量大脑功能图像。我们开发了一种从多通道脑电和脑磁图数据以及从语音和身体表情中提取个性的方法。我们提出了一个基于投射到大脑-名人脑系统的神经递质和调节剂的贡献的个性模型。我们应用语音和身体运动的互相关分析来量化诊断特征和紊乱模式。我们构建了一个测试和治疗中大脑功能和行为数据的综合数据库，以应用对思维和人格障碍的主观和量化评估。

We investigated and got following results on the development of objective evaluation method for thought and personality disorders as well as for treatments including SST(social skill training)based on four types of personality-related data, i.e., brain activity data, results from mental test, behavioral pattern in dialogue, cognitive impression on mental states emerged from subjects.extraction method of individuality in spoken language and thought process.1. We analyzed brain metabolic data from blood metabolities of neuromodulators as candidates of individuality.2. We extracted individuality in multi-channel EEG and MEG topographies which are related to linguistic and thought process.3. We measured diagnostic behaviors of thought and personality disordered patients in treatments.4. We found individuality and abnormality in MR images of cortico-subcortical system.5. We improved mental and psychological tests to be a computer-controlled testing system with simultaneous measuring of brain functional images.6. We developed a method for extracting individualities from multi-channel EEG and MEG data as well as from speech and body expression.7. We presented a model on individuality on the basis of contributions of neurotransmitters and modulators projected to cerebro-celebellar system.8. We applied cross-correlation analysis on speech and body movements to quantify diagnostic characteristics and disordered patterns.9. We constructed a integrated database of brain functional and behavioral data in tests and treatments to apply subjective and quantified evaluation of thought and personality disorders.