personalized medicine of implants based on biomechanics simulation

本研究的目的是发展个体种植体治疗，以明确插入扭矩与骨质量的相关性，确定上部结构的设计，并评估种植体周围骨结构随时间的定量观察。该研究表明，通过口内x线片评估的骨量插入扭矩与弹性模量之间存在显著的正相关，该评估技术可用于在植入种植体之前简单定量地预测种植体的初级稳定性。此外，在上部结构的设计中，观察了顶角，明确了桥台产生的张拉力。因此，考虑到每个个体的生物力学的上层结构的制造是实现的。接下来，我们将测试通过检查口腔内x线片的结构参数来评估种植体周围骨结构系列变化的可能性。本研究表明，通过监测口腔内x线片记录的骨小梁结构参数的变化，可以间隔一段时间评估种植体周围骨结构的变化。如果骨小梁结构参数的变化是由种植体的过度负荷引起的，那么通过监测这些变化可以预测骨整合的损失，从而提供更可预测的种植体治疗。

The purpose of this study was to develop the individual implant treatment to clarify the correlation between insertion torque and bone quality and determine design of the superstructure and assess quantitive observation of peri-implant bone stracture with time. This study suggests that significant positive correlation were found between insertion torque for bone mass and elastic modulus as evaluated by intraoral radiographs and this evaluation technique may be used to simply and quantitatively to anticipate implant primary stability prior to implant placement. Moreover regarding design of the superstructure, the cusp angle is observed, tensible force produced in abutment was able to be clarified. Thereby, manufacture of the superstructure in consideration of the biomechanics of each individual was attained. To the next we test the possibility of evaluating serial change in peri-implant bone structures by examining structural parameters in intraoral radiographs. This study suggest that changes in peri-implant bone structure can be evaluated at intervals by monitoring the changes in structural parameter of trabecular bone as recorded in intraoral radiographs. If changes in structural parameters of the trabecular bone caused by excessive loading on implants are clarified, loss of osseointegration may be anticipated by monitoring the changes providing more predictable implant treatment.