A new biomechanical analyzing system based on the three-dimensional bone-implant interface structure around the implant.

本研究的目的是在体内明确种植体周围的三维骨结构，并建立一种新的生物力学分析系统。作者将这项研究作为流动进行。将3个羟基磷灰石涂层种植体（“种植体”）植入3只雌性成年猴的下颌无牙区，在植入前3个月将P_2M_1， M_1P_2， P_1P_2去除。3个月后处死，切除下颌骨。将含有植入物的组织块包埋在聚酯树脂中。该砌块每隔75 μ m由磨床按轴齿方向连续研磨。将块体的每个序列表面放在轮廓投影仪上，并对种植体周围的骨结构进行跟踪。这些数字化的数据是用个人计算机计算出来的。通过计算机绘图完成了种植体周围骨的三维结构。定量分析种植体表面0 ~ 75、75 ~ 150、150 ~ 225、225 ~ 300 μ m区域的骨接触率（bone contact ratio， BCR）和骨体积比（bone volume ratio， BVR）。通过在种植体表面铺设各区域的骨面积，生成骨结构模拟图像。种植体全面BCR分别为80.9、68.1、68.8%，各区域BVR均为60-70%。模拟图像显示了三维骨骼结构。这些结果提供了更详细的骨-种植体界面信息，并为开发新的生物力学分析系统提供了可能性。

The purpose of this study was to clarify the three-dimensional bone structure around the implant in vivo and to develop a new biomechanical analyzing system. The authors carried out this study as flows. Three hydroxyapatite-coated dental implants ( "Implant" ) were inserted into the mandibular edentulous areas of 3 female adult monkeys where P_2M_1, M_1P_2, P_1P_2 were removed 3 months before insertion. After 3 months, the monkeys were sacrificed and the mandibles were removed. Tissue block containing the implant was enbedded in polyester resin. This block was ground every 75 mu m serially in buccolingual direction by a grinding machine. Each serial surface of the block was put on the profile projector and the structure of the bone around the implant was traced. These digitized data were calculated with a personal computer. A three-dimensional structure of bone around the implant was completed by computer graphics. The bone structure was analyzed quantitatively, as bone contact ratio (BCR) and bone volume ratio (BVR) in each region of 0-75, 75-150, 150-225, 225-300 mu m from implant surface. Simulated images of bone structure were also produced by laying bony area of each region from implant surface. BCR around the whole implant surfaces were 80.9, 68.1, 68.8%, and BVR were 60-70% in all regions. Simulated images revealed three-dimensional bone structure. These results provide more detailed informations on bone-implant interface and a possibility to develop new biomechanical analyzing system.