Development of pierce tube in solid cancer

本研究的目的是研制组织穿刺管附弯针，并试制用于光动力治疗和动物实验的高输出半导体激光器.组织内穿刺管附弯针的研制我们尝试从目录中查找可能存在于活体中的材料。我们进行了聚乙烯醇和聚丙烯材料制管试验，并进行了动物实验。但任何管子都不起作用。我们已经想到了更好的玻璃材料，它可以在组织中形成。但是肌肉已经被玻璃材料的腐蚀作用破坏了。因此，生物体受到了玻璃的伤害，神经和血管。所以我们想到了使用水解的材料和形状记忆合金。但是它们干扰了激光的传输，而且价格昂贵.用于光动力治疗的高输出半导体激光器的试制及动物实验我们用雄性家兔对移植性癌细胞VX 2进行了光动力治疗实验。试制的高输出半导体激光器的弱功率比准分子染料激光器的弱功率要小，但如果我们对这台机器加以改进，我们认为可以更好地利用试制的高输出半导体激光器进行光动力学治疗。

The purpose of this study has be development of pierce tube attached curving needle in tissue and trial production of a high output semiconductor laser for photodynamic therapy and animal experiment.1. Development of pierce tube attached curving needle in tissue.We have tried to look up possible materials in living body from catalogs. We tested to made tubes of polyvinyl alcohol and polypropylene, and to be producted tubes at animal experiment. But any tubes have not worked. We have thought better material of glass that meintain form in tissue. But a muscle has be destroyed by the constraction of the material of glass. So living body has be injured nurve and vessel by the glass. And so we have thought to use the material of hydrolysis and of a shape-memory alloy. But they have disturbed transmission of laser and be expensive.2. Trial producution of a high output diode laser for photodynamic therapy and animal experiment.We have experimented on photodynamic therapy that used male rabbits at transplanted cancer cell "VX2". Trial production of a high output diode laser has be less weak power than excimer dye laser, but if we will improved on the machine, we have thought to be able to make better use of trial producution of a high output diode laser for photodynamic therapy.