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Nanoprobe and Microprobe Spectroscopic Techniques in Drug Design, Probing Mechanisms of Diseases, and Bioinorganic Chemistry

Nanoprobe and Microprobe Spectroscopic Techniques in Drug Design, Probing Mechanisms of Diseases, and Bioinorganic Chemistry
药物设计、疾病探测机制和生物无机化学中的纳米探针和微探针光谱技术
批准号:
DP0346162
负责人:
Prof Peter Lay
金额:
$19.24万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2003
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2003-03-01 至 2006-02-28

项目摘要

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中文摘要
翻译
纳米探针和微探针光谱技术提供了无与伦比的机会来探测药物、致癌物和生物分子在培养细胞和组织中的结构和分布。这些技术代表了在分子水平上了解体内代谢过程的新领域,并提供了有关药物和毒素的代谢和分布的前所未有的信息,这些药物和毒素与癌症等疾病的治疗和病因有关。该项目旨在推动纳米探针和微探针(x射线吸收、SRIXE、PIXE、拉曼和双光子荧光)技术在这些应用中的应用。
英文摘要
Nanoprobe and microprobe spectroscopic techniques offer unparalleled opportunities to probe the structures and distributions of drugs, carcinogens, and biomolecules in cultured cells and tissues. Such techniques represent new frontiers in understanding in vivo metabolic processes at the molecular level, as well as providing unprecedented information on the metabolism and distributions of pharmaceuticals and toxins involved in the treatment and cause of diseases, such as cancer. This project is aimed at pushing the boundaries of nanoprobe and microprobe (X-ray absorption, SRIXE, PIXE, Raman and two-photon fluorescence) techniques for such applications.
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Metal Virulence and Therapeutic Factors in Pathogen Bioinorganic Chemistry
  • 批准号:
    DP210101632
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $42.2万
  • 财政年份:
    2021
  • 负责人:
    Prof Peter Lay
  • 依托单位:
Rapid Molecular (Bio)material Imaging by Infrared and Raman Microscopies
  • 批准号:
    LE200100043
  • 项目类别:
    Linkage Infrastructure, Equipment and Facilities
  • 资助金额:
    $25.94万
  • 财政年份:
    2020
  • 负责人:
    Prof Peter Lay
  • 依托单位:
Bioinorganic chemistry between immune cell and pathogen
  • 批准号:
    DP180102741
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $37.48万
  • 财政年份:
    2018
  • 负责人:
    Prof Peter Lay
  • 依托单位:
Roles of Metal Complexes in Carbohydrate Metabolism – Anti-Diabetic Drugs
  • 批准号:
    DP160104172
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $34.92万
  • 财政年份:
    2016
  • 负责人:
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  • 依托单位:
海外基金