Search for traditional medicines in Thailand and scientific evaluation of their pharmacological effects

在泰国，许多传统药物用于治疗和促进健康。根据与泰国同事的讨论，我们慷慨地提供了一些泰国植物提取物和纯化化合物。考察了这些提取物和化合物的药理作用；特别是对抗癌耐药肿瘤细胞的作用。发现某些提取物增强了药物的抗癌作用，而另一些提取物本身具有潜在的抗癌作用。这些结果将为开发新的抗癌化学疗法提供重要信息。

In Thailand, many traditional medicines are used for therapy and health promotion. Based on the discussion with colleagues in Thailand, some Thai plant extracts and purified compounds were generously provided. The pharmacological effects of these extracts and compounds were examined ; especially the effects on anticancer drug-resistant tumor cells. It was found that certain extracts potentiated the effect of anticancer effect of the drug, while another extract has potential anticancer effect by itself. These results would provide important information for the development of novel anticancer chemotherapies.