Pathogen recognition and initial immune responses related to pattern recognition receptors in marine bivalves mollusks

本研究部分阐明了海洋双壳类对病原体的识别和早期免疫反应的机制。简而言之，海洋双壳类太平洋牡蛎拥有多种病原体识别受体(PRR)蛋白，并在PRR识别病原体后启动免疫反应。类似的防御方式在其他无脊椎动物中也有报道，但太平洋牡蛎中的一些PRR蛋白具有高度特征性的结构。基于这些发现，人们认为海洋双壳类的识别和早期免疫反应可能与节肢动物等其他无脊椎动物的已知机制相似但不完全相同。

This research project partially elucidated the mechanisms of pathogen recognitions and early immune responses against recognized pathogens in marine bivalves. Briefly, a marine bivalves, Pacific oyster, possesses various pathogen recognition receptor (PRR) proteins, and starts immune reactions after PRR recognize pathogens. Similar defense manners have been reported from other invertebrates, but some PRR proteins in Pacific oyster have highly characteristic structures. Based on these findings, it is considered that recognition and early immune response in marine bivalves may be similar but not identical to known mechanisms in other invertebrates such as arthropods.