Training Program in Organogenesis

摘要 生物医学科学的快速发展和技术变化要求我们确定 帮助下一代科学家驾驭复杂环境的战略 科学学科之间流畅的沟通和合作是取得成功的关键。 器官发生中心(CFO)成立于1995年，旨在统一基础、应用和临床 科学家们有一个共同的目标：了解构成器官和 组织的形成，并利用这些知识来创造持久的人造器官，改善 干细胞疗法和有效的器官移植系统，将纠正获得性和 遗传性人类疾病。器官发生培训计划于19年前启动 作为首席财务官教育使命的组成部分。它的主要目标是提供 器官发生领域的智力和技术培训，并促进 通过让受训者接触到研究和研究导师，从而实现跨学科参与 跨越临床、基础和应用科学之间的界限。这些目标是 通过鼓励双导师结构进行研究、培训和 受训人员参加若干培训活动，包括参加正式的 器官发生课程，器官发生研讨会系列，双月培训会议，双月 一年一度的国际研讨会和定期的相声系列，我们在其中配对一名临床医生 和基础科学家共同介绍一个共同的器官或疾病/障碍。所有受训人员 此外，还参与了生物艺术学，这是一个社区外展计划，在那里，艺术、科学和 公共教育相结合。每个实习生都可以选择与临床合作伙伴配对 同意促进他们接触临床科学、临床管理的导师 学员研究领域中的患者及其健康挑战。这是一次竞争性更新 请求继续为5个博士后培训时段和3个博士后培训时段(1个专门 目标是医学博士)。受训人员主要来自所列38个实验室 培训计划的导师。参与的教职员工来自15个系和4个系 密歇根大学的学校(医学院、工程学院、 文理文科及牙科学院)。该计划由内部一名 咨询委员会和业务委员会，以及两名外部顾问(布拉德利博士 Yoder博士，阿拉巴马大学伯明翰分校博士，Richard Behringer博士，MD Anderson博士) 以确保其对不断变化的研究环境的持续反应。

ABSTRACT The rapid advancement and technical changes in biomedical science requires that we identify strategies to help the next generation of scientists navigate a complex landscape in which fluent communication and collaboration between scientific disciplines is essential for success. The Center for Organogenesis (CFO) was formed in 1995 to unite basic, applied and clinical scientists with a common goal: to understand the basic mechanisms that underlie organ and tissue formation, and to use this knowledge to create long-lasting artificial organs, improve stem cell therapies and effective organ transplantation systems that will correct acquired and inherited human disease. The Training Program in Organogenesis was initiated 19 years ago as an integral part of the educational mission of the CFO. Its main goals are to provide intellectual and technical training in the field of organogenesis, and to promote interdisciplinary engagement by exposing trainees to research and research mentors that cross boundaries between clinical, basic and applied sciences. These goals are accomplished by encouraging a two-mentor structure for research training and the involvement of trainees in several training activities that include participation in a formal course in Organogenesis, an Organogenesis Seminar series, bimonthly training meetings, bi- annual International Symposia, and a regular CrossTalk series, in which we pair a clinician and basic scientist to jointly present on a common organ or disease/disorder. All trainees additionally engage in BioArtography, a community outreach program where art, science and public education are combined. Each trainee is offered the option of pairing with a clinical co- mentor who agrees to facilitate their exposure to clinical science, clinical management of patients and their health challenges in the trainee's research area. This competitive renewal requests continued funding for 5 predoctoral and 3 postdoctoral training slots (one specifically targeted to an MD fellow). Trainees come primarily from the laboratories of the 38 listed mentors of the Training Program. Participating faculty come from 15 departments and 4 schools across the University of Michigan (Medical School, College of Engineering, College of Literature, Sciences & Arts and Dental School). The Program is monitored by an internal Advisory Board and Operating Committee, and also by two External Advisors (Drs. Bradley Yoder, PhD, University of Alabama-Birmingham, and Richard Behringer, PhD, MD Anderson) to ensure its continued responsiveness to an evolving research environment.