Project-005

中心研究能力计划的主要目标是支持创新研究并提供 研究人员进行安全、高质量翻译研究的必备工具。正如RFA中概述的那样，这 CTSA的组成部分将专注于整合特殊人群(ISP)以及参与者和临床 交互(PCI)。 我们的互联网服务提供商核心拥有广泛的资源，可以在不同的年龄段进行翻译研究，包括 不限于儿童、老年人、孕妇和新生儿(母胎医学)，以及 西班牙裔人口。此外，UTMB在调查罕见的孤儿疾病方面拥有丰富的专业知识 如卟啉症、肥大细胞病等，以及对当前美国流行、阿片类药物使用和成瘾的研究 行为(可选集线器)。我们独家配备了最先进的疫苗开发中心 预防性护理的关键环节。我们的目标是成为运营商，将利用现有的个人计划优势来 共同扩大我们在多中心试验和服务不足社区的覆盖面。互联网服务供应商的核心将是 与网络容量和信息学密切相关。 PCI核心将把重点放在临床医生研究教育上。具体地说，关于加强 进行高质量翻译研究的安全性和效率。向前看(AIMS)，临床试验 将通过整合研究教练、培训和对新的临床研究的支持来扩大规模，并提供 调查人员指导我们的一个新的卫星演播室。与信息学数据协调中心合作， PCIcore将为以下方面提供新培训、监测和监管方面的质量控制部分 多点临床试验。此外，UTMB继续发展成为一个更大的社区区域。为此， 我们将扩大UTMB的临床研究中心(CRC)的足迹及其人体研究安全计划。至 为了帮助实现这些目标，PCI核心将利用临床研究办公室、临床研究 并与翻译工作和劳动力发展有着密切的联系。

The primary goal of the Hub Research Capacity program is to support innovative research and to provide the requisite tools for investigators to perform safe, high quality translational research. As outlined in the RFA, this component of the CTSA will focus on Integrating Special Populations (ISP) along with Participant and Clinical Interactions (PCI). Our ISP core has extensive resources for performing translational research in various age groups including but not limited to children, older adults, pregnant women and neonates (maternal-fetal medicine), as well as Hispanic populations. Additionally, UTMB has tremendous expertise for investigating rare, orphan diseases such as porphyria, mast cell disease etc. and research on the current US epidemic, opiate use and addictive behaviors (Optional HUB). We are exclusively equipped with a state-of-the-art vaccine development center as a critical arm of preventative care. Our Aim for ISP, will capitalize on existing individual program strengths to collectively broaden our outreach in multicenter trials and underserved communities. The ISP core will be intimately linked with Network Capacity and Informatics. The PCI core will focus its efforts on clinician research education. Specifically, on novel methods to enhance the safety and efficiency for conducting high quality translational research. Moving forward (Aims), clinical trials will be augmented by integrating study coaches, training and support for new clinical studies as well as provide investigators guidance to one of our new satellite studios. Working with Informatics Data Coordinating Center, the PCI core will provide quality control component for new training, monitoring and regulatory aspects for multi-site clinical trials. Additionally, UTMB continues to grow into a larger community area. Towards this end, we will extend UTMB’s Clinical Research Center (CRC) footprint and its human research safety program. To help accomplish these aims, the PCI core will utilize the Office of Clinical Research, the Clinical Research Center (CRC) as well as have strong links with Translational Endeavors and Workforce Development.