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Understanding how a family of chloride pumps and channels are regulated

Understanding how a family of chloride pumps and channels are regulated
了解如何调节一系列氯泵和通道
批准号：
DP150100673
负责人：
Prof Michael Parker
金额：
$51.87万
依托单位：
The University of Melbourne
依托单位国家：
澳大利亚
项目类别：
Discovery Projects
财政年份：
2015
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2015-01-01 至 2019-12-31
来源：
https://dataportal.arc.gov.au/RGS/Web/Grants/DP150100673
关键词：
Understandinghowfamilychloridepumps

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英文摘要
This project examines how a major family of chloride channels and pumps, found in nearly all organisms, works at the molecular level and how it is modulated by chemical signals from within cells. The expected outcomes are to demonstrate novel mechanisms general to these essential proteins and to provide fundamental insights in understanding vital physiological processes across all kingdoms of life. Ultimately, this work aims to lead to the development of novel engineered proteins that can act as sub-microscopic electrical 'switches' and highly specific sensors for a variety of molecules for nanotechnology and biotechnology applications.
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