Comparative analysis of novel transgenic mouse models for brain and islet amyloidoses

我们的目的是了解两种高度流行的疾病，大脑疾病阿尔茨海默病（AD）和代谢紊乱2型糖尿病（DM），有什么共同点。通过了解发病机制和新型转基因模型的发展，我们的长期研究目标是确定新的药物靶点，开发筛选试验和专利新的发现。总的来说，这有望导致AD和DM药物的产生，并减少这两种使人衰弱的疾病的社会经济负担。

We aim to understand what two highly prevalent diseases, the brain disorder Alzheimer's disease (AD) and the metabolic disorder Type 2 Diabetes mellitus (DM), have in common. Through understanding pathogenesis and the development of novel transgenic models our long-term research goal is to identify new drug targets, to develop screening assays and to patent new findings. Collectively, this hopefully leads to AD and DM drugs and reduces the socio-economic burden of both debilitating diseases.