Coronary atherosclerosis and its relationship with platelet activation

血栓是心脏病发作的关键，每年有成千上万的澳大利亚人死于心脏病发作。血小板是血液中的细胞，在血栓的形成中起着至关重要的作用，而冠心病与血小板激活有关。这项研究将探讨人类心脏动脉中血小板激活的性质，它与炎症细胞激活的关系，以及与人类心脏动脉狭窄的严重程度的关系。

Blood clots are critical to the development of heart attacks, which kill many thousands of Australians annually. Platelets are cells in the blood that play an essential role in formation of blood clots, and coronary disease is associated with platelet activation. This research study will investigate the nature of platelet activation in the arteries of the human heart, its relationship to activation of inflammatory cells, and to the severity of narrowings in the arteries of the human heart.