PHYSIOLOGICAL AND CYTOCHEMICAL PATHOLOGY OF PARASITIC DISEASES

抗锥虫溶解因子（ATF-II）的纯化研究 从细菌种类荧光假单胞菌中分离。 一 采用反相高效液相色谱法， 高效液相色谱法，是一项专利的主题， 正在处理的美国专利审查申请 办公室 结构的质谱和NMR研究 活性化合物的表征仍在继续。 的 化学结构的确定是必不可少的， 合成开始，药理学和毒理学性质 采用克氏锥虫感染进行检查。

Studies on the purification of a lytic anti-trypanosomal factor (ATF-II) from the bacterial species, Pseudomonas fluorescens, were continued. A purification procedure was developed employing reversed-phase high performance liquid chromatography and was the subject of a patent application which is being processed for review by the U.S. Patent Office. Mass spectroscopic and NMR studies on the structural characterization of the active compound are being continued. The determination of chemical structure is essential before studies on synthesis are initiated and pharmacological and toxicological properties are examined employing Trypanosoma cruzi infections.