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ENDOTHELIAL FENESTRATIONS OF THE ALVEOLAR CAPILLARIES IN FIBROTIC LUNG DISORDERS

ENDOTHELIAL FENESTRATIONS OF THE ALVEOLAR CAPILLARIES IN FIBROTIC LUNG DISORDERS
纤维化肺疾病中肺泡毛细血管的内皮开窗
批准号:
3843448
负责人:
V J FERRANS
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至

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中文摘要
翻译
肺活检标本的电子显微镜研究揭示了 开窗型肺泡毛细血管(含 隔膜状开口或细胞质中的窗孔) 患有各种肺纤维化疾病的患者。这样的毛细血管是 通常存在于支气管粘膜,但不存在于肺泡。考虑因素是 考虑到这种表型变化代表着一种 类似于肺泡的化生过程 纤维性肺疾病中的上皮细胞。
英文摘要
Electron microscopic studies of lung biopsy specimens reveal the presence of pulmonary alveolar capillaries of the fenestrated type (containing diaphragm-like openings or fenestrae in their cytoplasm) in 20 of 28 patients with a variety of fibrotic lung disorders. Such capillaries are normally present in bronchial mucosa, but not in alveoli. Consideration is given to the possibility that this phenotypic change represents a metaplastic process analogous to that which occurs in pulmonary alveolar epithelium in fibrotic lung disorders.
期刊论文(1)
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会议论文
Characterization of alpha 2-adrenergic receptor subtype-specific antibodies.
α2-肾上腺素能受体亚型特异性抗体的表征。
DOI: --
发表时间: 1993
期刊: Molecular pharmacology
影响因子: 3.6
作者: [Kurose,H, Arriza,JL, Lefkowitz,RJ]
通讯作者: Lefkowitz,RJ
SURGICAL PATHOLOGY OF THE CARDIOVASCULAR SYSTEM
ULTRASTRUCTURE AND FUNCTION OF THE MYOCARDIUM--AN OVERVIEW
INTRALUMINAL FIBROSIS IN FIBROTIC LUNG DISORDERS
LIPID ACCUMULATION IN VENOUS BYPASS GRAFTS--INFLUENCE OF ARTERIAL PRESSURE
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