A new monocyte atherogenic phenotype in chronic HIV disease.

在澳大利亚，大多数HIV阳性的人死于由动脉粥样硬化或冠状动脉增厚引起的心血管疾病。一种被称为单核细胞的白细胞预防动脉粥样硬化的能力在HIV感染中受损。这个项目旨在了解艾滋病毒是如何做到这一点的，以及我们如何扭转这种影响。了解这些过程也将有助于改善治疗方法，以减少患有其他慢性炎症疾病的人患心脏病的几率。

Most HIV+ people in Australia now die from cardiovascular disease, caused by atherosclerosis or thickening of coronary arteries. The ability of a white blood cell called the monocyte to prevent atherosclerosis is impaired in HIV. This project aims to understand how HIV does this and how we can reverse the effect. Understanding these processes will also help improve treatments to reduce heart disease in people with other chronic inflammatory conditions.