CORE--BIOSTATISTICS COMPONENT

本项目研究项目的最终目标 应用是为了改善患者的治疗效果， 白血病和淋巴瘤。 为了实现这一目标，实验室 研究将用于为开发新的治疗方法提供基础。 在诊所的方法。 这个项目成功的重要因素是 与本核心中的个人进行生物统计学合作， 数据的计算机化输入和质量保证，并协助设计 临床，实验室和动物研究项目的分析。 生物统计核心的目的是提供以下服务 所有的研究项目都会用到。 1. 为临床研究提供生物统计协作 协议. 这包括设计、执行、分析和 报告临床方案。 2. 为动物和实验室提供生物统计合作 调查研究。 这包括设计，行为， 分析和报告这些研究，包括协调 实验室结果与临床研究的参数和结局。 3. 监督数据处理和数据质量保证， 协调数据专家的工作和数据的工作 管理人员维持一个准确的计算机化数据库。 4. 提供一名数据专家，负责维护计算机化数据库， 确保质量控制和标准化报告。 5. 为数据处理、表单设计和 统计分析。 6. 定期审查跟踪流程的功能，以确保 及时接收和分发标本。 7. 确保研究实验室结果的计算机化记录 标本

The ultimate objective of the research projects in this program project application is to improve the therapeutic results for patients with leukemia and lymphoma. To achieve this objective, results of laboratory studies will be used to provide the basis for development of new treatment approaches in the clinic. Important for the success of this project is the biostatistical collaboration with individuals in this Core who provide computerized entry and quality assurance of data, and assist in the design and analysis of clinical, laboratory, and animal research projects. The purpose of the Biostatistics Core is to provide the following services that will be utilized by all of the research projects. 1. To provide biostatistical collaboration for clinical research protocols. This includes all aspects of the design, conduct, analysis, and reporting of the clinical protocols. 2. To provide biostatistical collaboration for animal and laboratory research studies. This includes all aspects of the design, conduct, analysis, and reporting of such studies, including the coordination of laboratory results with parameters and outcomes from the clinical studies. 3. To supervise data processing and data quality assurance, and to coordinate the efforts of the data specialist and those of the data managers in maintaining an accurate computerized database. 4. To provide a data specialist to maintain a computerized database, with assured quality control and standardized reporting. 5. To provide computing resources for data processing, forms design, and statistical analyses. 6. To periodically review the function of the tracking process, to insure that specimens are being received and distributed in a timely fashion. 7. To assure computerized recording of laboratory results on research specimens.