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Statistical genetic analysis of coronary artery disease

Statistical genetic analysis of coronary artery disease
冠心病的统计遗传学分析
批准号:
6681714
负责人:
ALEXANDER F WILSON
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至

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中文摘要
翻译
该项目的目标是测试候选基因中潜在的功能多态与家族数据中的心血管相关结果(如血压)之间的关联。数据包括来自韩国的717个观测数据(87个家系)。在分析之前,个人和家庭的身份识别号码是随机的,以确保保密。后代对中亲的回归(ROMP)方法将被用来检验和估计总体性状遗传力和可归因于候选基因座的遗传力。候选基因的鉴定可能有助于阐明该人群心血管疾病的病因。
英文摘要
The goal of this project is to test for association between potentially functional polymorphisms in candidate genes and cardiovascular related outcomes, such as blood pressure, in family data. The data consist of 717 observations (87 pedigrees) from Korea. The individual and family identification numbers were randomized prior to analysis to ensure confidentiality. The Regression of Offspring on Mid-Parent (ROMP) method will be used to test for association and estimate the overall trait heritability and the heritability attributable to the candidate loci. Identification of a candidate gene may help to elucidate the etiology underlying cardiovascular disease in this population.
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SEGREGATION/LINKAGE ANALYSIS FOR HYPERTENSION
  • 批准号:
    3339900
  • 项目类别:
  • 资助金额:
    $7.65万
  • 财政年份:
    1982
  • 负责人:
    ALEXANDER F WILSON
  • 依托单位:
A STUDY OF SEGREGATION/LINKAGE ANALYSIS FOR HYPERTENSION
  • 批准号:
    3339897
  • 项目类别:
  • 资助金额:
    $7.06万
  • 财政年份:
    1982
  • 负责人:
    ALEXANDER F WILSON
  • 依托单位:
A STUDY OF SEGREGATION/LINKAGE ANALYSIS FOR HYPERTENSION
  • 批准号:
    3339899
  • 项目类别:
  • 资助金额:
    $7.35万
  • 财政年份:
    1982
  • 负责人:
    ALEXANDER F WILSON
  • 依托单位:
A STUDY OF SEGREGATION/LINKAGE ANALYSIS FOR HYPERTENSION
  • 批准号:
    3339898
  • 项目类别:
  • 资助金额:
    $7.4万
  • 财政年份:
    1982
  • 负责人:
    ALEXANDER F WILSON
  • 依托单位:
海外基金