PRE-DOCTORAL TRAINING IN CARDIOVASCULAR BIOLOGY

这项申请超出了所提供的空间，是为了申请佐治亚医学院(MCG)新的综合心血管生物学多学科博士前培训补助金。该项目的长期目标是利用分子、遗传学、细胞、组织/器官、整体动物和人体实验方法，为心血管综合生物学领域的独立研究事业培养博士前和医学博士/博士研究生。该项目涉及CELT生物和解剖学、内科、病理学、儿科、药理学和毒理学、生理学、外科等系的20多名教师的专业知识。这些教师中的大多数还受聘于佐治亚州预防研究所、分子医学和遗传学研究所、血管生物学中心以及MCG园区的生物技术和基因组医学中心。该项目的教授代表了一群杰出的综合心脏和血管生物学家，他们的研究兴趣涵盖五个相关的心血管领域：1)血管CETL信号，2)血管张力控制，3)心脏发育，4)内皮功能障碍，5)心血管疾病预防。这笔培训补助金将通过医学院的血管生物学中心进行管理。该项目由项目主任大卫·M·波洛克博士和项目联席主任珍妮弗·S·波洛克博士领导，他们都是知名研究人员。波洛克博士是外科、生理学、药理学和毒理学系的副教授，是血管生物学中心的成员，也是研究生院课程和进步委员会的主席。波洛克博士是药理学和毒理学以及生物化学和分子生物学系的副教授，血管生物学中心成员，研究生院血管生物学研究生项目主任。一个由佐治亚医学院研究生项目经验丰富的领导人组成的内部咨询委员会将监督该项目。受训者将是目前在佐治亚州医学院研究生院生物医学博士项目全日制注册的博士或医学博士研究生。学生将根据他们对综合心血管生物学表现出的兴趣以及他们以前的学术表现和研究经验来选择。该培训计划将包括第一年的两名博士前学生，第二年和第三年将增加两名学生，三到五年最多六名学生。所有学员将被要求参加教学培训活动，包括第一年核心课程并通过第一次资格考试；高级选修课，包括心血管生理学和药理学；科学传播和研究伦理课程，以及生物统计学；参加一个或多个系系列研讨会；心血管杂志俱乐部；以及每年的研究生研究日活动。负责招聘的助理院长将领导一项努力，以增加接受心血管研究培训的人数不足的少数族裔和妇女人数。研究培训设施包括教官的个人实验室，参与部门、中心和研究所的核心实验室，以及生物遥测、分子生物学、组织学、转基因分析、转基因和胚胎干细胞、流式细胞术和CELT成像方面的杰出机构核心设施，在三个相连的建筑中包含超过100,000平方英尺的研究空间。完成该计划后，学生将准备在一流实验室进行博士后培训，开始他们的职业生涯，成为心血管科学的独立调查人员。表演网站========================================Section End===========================================

EXCEED THE SPACE PROVIDED, This application is for a new multidisciplinary pre-doctoral training grant in integrative cardiovascular biology at the Medical College of Georgia (MCG). The long-term objective of this program is to train pre- doctoral Ph.D. and M.D./Ph.D. students for independent research careers in integrative cardiovascular biology, utilizing molecular, genetic, cellular, tissue/organ, whole animal and human experimental approaches. This program involves the expertise of over 20 faculty in the Departments of Celt Biology & Anatomy, Medicine, Pathology, Pediatrics, Pharmacology & Toxicology, Physiology, Surgery. A majority of these faculty also have appointment or affiliations with the Georgia Prevention Institute, the Institute for Molecular Medicine and Genetics, the Vascular Biology Center, and the Center for Biotechnology and Genomic Medicine on the MCG campus. The faculty preceptors of the program represent an outstanding group of established integrative cardiac and vascular biologists whose research interests cover five related cardiovascular areas: 1) vascular cetl signaling, 2) control of vascular tone, 3) cardiac development, 4) endothelial dysfunction, and 5) prevention of cardiovascular disease. This training grant will be administered through the Vascular Biology Center in the School of Medicine. The program is directed by Dr. David M. Pollock, Program Director and Dr. Jennifer S. Pollock, Program Co- Director, both established investigators. Dr. D. Pollock is an Associate Professor in the Departments of Surgery, Physiology, and Pharmacology & Toxicology, a member of the Vascular Biology Center, and the Chair of the Curriculum and Advancement Committee in the School of Graduate Studies. Dr. J. Pollock is an Associate Professor in the Departments of Pharmacology & Toxicology and Biochemistry & Molecular Biology, a member of the Vascular Biology Center, and Director of the Vascular Biology Graduate Program in the School of Graduate Studies. An Internal Advisory Committee of experienced leaders of the graduate program at the Medical College of Georgia wilt supervise the program. Trainees will be Ph.D. or M.D.IPh.D. graduate students currently enrolled full-time in the Biomedical Sciences Ph.D. program in the Medical College of Georgia School of Graduate Studies. Students will be selected based on their expressed interest in integrative cardiovascular biology and their previous academic performance and research experience. The training program will include two pre-doctoral students in the first year with an additional two students being added in both the second and third years for a maximum of six students for years three through five. All trainees will be required to participate in didactic training activities, which consist of the first year core curriculum and passing the first qualifying exam; an advanced course electives including Cardiovascular Physiology & Pharmacology; courses in Scientific Communications and Research Ethics, and Biostatistics; attendance in one or more departmental seminar series; the cardiovascular journal club; and the annual Graduate Research Day activities. The Assistant Dean for Recruitment will lead an effort to increase the number of underrepresented minorities and women who receive training in cardiovascular research. Facilities for research training include the individual laboratodes of the preceptors, and the core laboratories of the participating department, centers, and institutes, as well the outstanding institutional Core Facilities in Biotelemetry, Molecular Biology, Histology, Transgenic Analysis, Transgenic and Embryonic Stem Cell, Flow Cytometry and Celt lmaging, encompassing in excess of 100,000 sq.ft, of research space in three contiguous buildings. Upon completion of the program, students will be ready to pursue post-doctoral training at premier laboratories as they begin their careers as i independent investigators in cardiovascular sciences. PERFORMANCE SITE ========================================Section End===========================================