Infrastructure Improvements for the Caribbean Primate R*

描述(由申请人提供)： 这项申请的目的是获得必要的基础设施改善资金，以提高加勒比灵长类研究中心Sabana Seca野外站的动物研究和护理质量。30多年来，CPRC一直在为科学界提供宝贵的服务，为健康的印度裔恒河猴提供已知背景和相同基因库的恒河猴，用于多种影响人类的疾病的研究。在2000年10月至2004年10月期间，CPRC为PHS和NIH赞助的研究项目提供了600多只猴子，预计对这种物种的需求将增加，用于生物医学和生物防御研究。拟议的建设是多阶段总体计划的组成部分，该计划旨在使中国红十字会的研究支持设施现代化，以便继续向研究人员提供足够的优质动物供应。拟议的项目包括建造一个新的兽医服务设施，以取代一个小而过时的诊所，升级电力基础设施，以及购买、安装和建造笼架洗涤器设施。拟议的翻修对动物护理和使用计划、对校内和校外调查人员的研究计划以及整个生物医学研究的预期影响是巨大的。这些改进将通过扩大和提高CPRC的能力来确保高质量的研究支持，以满足当前和预计的需求，为国家重要的生物医学、生物防御和行为研究计划提供恒河猴。

DESCRIPTION (provided by applicant): The purpose of this application is to obtain funds for essential infrastructure improvements to enhance the quality of animal research and care at the Sabana Seca Field Station of the Caribbean Primate Research Center (CPRC). For over 30 years the CPRC has been providing a valuable service to the scientific community by supplying healthy Indian-origin rhesus macaques with known backgrounds and of the same genetic pool for use in studies for numerous diseases that affect humans. For the period between October 2000 and October 2004, the CPRC provided over 600 monkeys to PHS and NIH-sponsored research programs and the demand for this species for biomedical and biodefense research initiatives is expected to increase. The proposed construction is an integral part of a multi-phase master plan to modernize the research support facilities of the CPRC in order to continue providing an adequate supply of quality animals to researchers. The proposed projects include the construction of a new veterinary services facility to replace a small and outdated clinic, the upgrade of the electrical infrastructure, and the purchase, installation and construction of a cage rack washer facility. The anticipated impact of the proposed renovations on the animal care and use program, on the research programs of intramural and extramural investigators, and on biomedical research overall, is substantial. These improvements will assure quality research support by expanding and improving the capability of the CPRC to meet current and projected needs to supply rhesus monkeys for biomedical, biodefense, and behavioral research initiatives of National importance.