Social Information Processing: Assessment Development

项目概述：这个R21项目的主要目的是为成人社会信息处理（SIP）的计算机综合评估开发视觉刺激。第二个具体目的是对这种增强的SIP评估与情绪信息处理（EIP）评估之间的关系进行初步研究。SIP关注社会交互的评估和处理中涉及的各种过程（其中许多是自动的）。长期以来，人们一直在外化障碍的儿童和青少年中研究SIP，其中已经证明了SIP中的群体多重缺陷（例如，社会线索编码减少，敌对归因偏见），特别是与儿童创伤和虐待以及攻击行为的发展有关。虽然这项工作导致了对儿童/青少年的一系列长期和富有成效的研究，但对成人SIP的研究却很少。这主要是因为缺乏足够的工具来评估成人SIP。在这个R21项目中，PI建议使用他已经开发的成人SIP短片作为开发一系列与SIP相关的视觉呈现刺激的基础。第一套视觉刺激，以“插图故事板”的形式，将被纳入基于计算机的演示平台（E-Prime），并在健康志愿者和间歇性爆发性障碍受试者中进行测试。如果这些视觉刺激在评估SIP的各个方面（特别是在SIP的第一步“编码”的情况下）被证明是有效的，那么这些刺激将被改编成简短的“视频片段”，然后在第二组健康志愿者和IED受试者中再次进行测试。将对“故事板”和“视频片段”进行一系列的信度和初步效度研究。这些研究包括内部一致性、重测信度、健康志愿者与IED组在SIP参数上的差异，以及与相关的收敛性和发散性测量（如自动敌对思想、攻击性、童年创伤史等）和情绪信息处理（识别面部情绪的准确性）的相关性。相关性：SIP是社会互动反应中产生攻击行为过程的关键组成部分。成人的SIP没有标准化的测量方法，也没有以受控方式进行的评估。此外，在成像环境中没有用于SIP评估的标准化刺激。这些措施的发展对于SIP的进一步科学研究及其在神经生物学研究中的整合至关重要。

DESCRIPTION (provided by applicant): Project Summary: The primary specific aim of this R21 project is to develop visual stimuli for a computer- based, comprehensive, assessment of Social Information Processing (SIP) in adults. The secondary specific aim is to perform a preliminary study of the relationship between this enhanced assessment of SIP and an assessment of Emotional Information Processing (EIP). SIP is concerned with the various processes (many of which are automatic) involved in the assessment and disposition of social interaction. SIP has long been studied in children and adolescents with externalizing disorders in which population multiple deficits (e.g., reduced encoding of social cues, hostile attribution bias) in SIP have been demonstrated, particularly in relation to childhood trauma and abuse and the development of aggressive behavior. While this work has led to a long and productive series of studies in children/adolescents, little work on SIP in adults has been done. This is largely because of a lack of adequate tools to assess SIP in adults. In this R21 project, the PI proposes to use the Adult SIP Vignettes he has already developed as the basis for the development of a series of visual presentation stimuli relevant to SIP. The first set of visual stimuli, in the form of "illustrated storyboards", will be incorporated onto a computer-based presentation platform (E-Prime) and tested in Healthy Volunteers and in subjects with Intermittent Explosive Disorder. If these visual stimuli prove effective in the assessment of the various aspects of SIP (especially in the case of the first SIP Step of "encoding"), the stimuli will then be adapted into brief "video clips", which will in turn be tested again in a second group of Healthy Volunteers and subjects with IED. A series of reliability and initial validity studies will be done for both the "storyboards" and the "video clips". These include studies of internal consistency, test-retest reliability, Healthy Volunteer vs. IED group differences in SIP parameters, and correlation with relevant convergent and divergent measures (e.g., automatic hostile thoughts, aggression, history of childhood trauma, etc.) and Emotional Information Processing (accuracy of identifying facial emotion). Relevance: SIP is a critical component to the process involved in generating aggressive behavior in response to social interaction. There are no standardized measures of SIP in adults and no assessment that is delivered in a controlled fashion. In addition, there are no standardized stimuli for SIP assessment that can be used in imaging environments. Development of such measures is critical for the further scientific study of SIP and for its integration in neurobiologhical research.