Research Training in Allergy and Immunology at Massachusetts General Hospital

描述（由申请人提供）：这是对哈佛医学院马萨诸塞州总医院过敏/免疫学新研究培训计划的再提交。该培训计划的目标是培养医学博士，医学博士/博士和博士博士后在过敏/免疫学研究方面的独立调查职业。我们的项目将以我们在成人和儿童过敏/免疫学方面非常成功的现有临床奖学金以及我们在基础科学过敏和免疫学研究方面强大的实验室项目为中心。在过去的五年中，MGH的过敏/免疫学部门发生了重大变化，这对我们的培训计划具有重要意义。在担任过敏/免疫科主任24年后，Kurt Bloch博士退休。2000年，Andrew Luster博士被任命为MGH风湿病、过敏和免疫学（DRAI）新部门的主任。这项新倡议的推动力是在医学部内设立一个司，重点研究人类疾病的免疫学和炎症基础。为了实现这一目标，建立了免疫学和炎症疾病中心（CUD）， Luster博士指导该中心作为DRAI的一部分，作为该司的基础科学基础。这个过敏/免疫学培训项目的目标是在有成就的教师的指导下提供有监督的实验室研究，以及通过课程和会议进行免疫学，分子生物学，遗传学和伦理问题的结构化培训。

DESCRIPTION (provided by applicant): This is a resubmission for a new research-training program in Allergy/Immunology at the Massachusetts General Hospital, Harvard Medical School. The goal of this training program is to train MD, MD/PhD and PhD post-doctoral fellows for independent investigative careers in Allergy/Immunology research. Our program will center on our highly successful pre-existing clinical fellowship in Adult and Pediatric Allergy/Immunology and our strong laboratory programs in basic science allergy and immunology research. There have been significant changes in the Allergy/Immunology Unit at the MGH over the last five years with important implications for our training program. After 24 years as Chief of the Allergy/Immunology Unit, Dr. Kurt Bloch retired, and in 2000, Dr. Andrew Luster was appointed Chief of a new Division of Rheumatology, Allergy and Immunology (DRAI) at the MGH. The impetus for this new initiative was to develop a Division within the Department of Medicine that would focus on the immunological and inflammatory basis of human disease. To accomplish this goal, the Center for Immunology and Inflammatory Diseases (CUD) was established, which Dr. Luster directs, as part of the DRAI, to serve as the basic science foundation for the Division. The goal of this Allergy/Immunology training program is to provide supervised laboratory research under the guidance of accomplished faculty members, along with structured training in immunology, molecular biology, genetics and ethical issues through courses and conferences. We have included only outstanding highly accomplished mentors with laboratories at MGH that are actively involved in basic science immunology research. Altogether, eight faculty members participate in this Allergy/Immunology training program as laboratory mentors, and five faculty members participate in the training program as clinical mentors. The participation of these faculty members offers an outstanding training opportunity in Allergy/Immunology research. We believe that we have created a balanced, integrated training program that will offer high quality training in laboratory science research in Allergy/Immunology that successfully integrates both MD and PhD trainees and basic science and clinical faculty. A T32 training program would have a dramatic effect on the Allergy/Immunology program at MGH and is critical to complete the transformation of this program from an excellent clinical program to a program that will produce the next generation of physician-scientists and PhD scientists committed to Allergy/Immunology research.