STUDENT LAB: INSULIN SENSITIVITY FOLLOWING EXERCISE & HIGH FAT OVERFEEDING

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。胰岛素是一种由胰腺分泌的激素，可以降低血糖。胰岛素降低血糖的能力在2型糖尿病中降低，并且在其他情况下也降低，包括高血压，肥胖和一些血脂紊乱。此外，胰岛素降低血糖的能力随着吃大量脂肪而降低，并随着运动而提高。我们做这个实验是为了向一年级的医学生展示高脂肪饮食和运动对胰岛素作用的不同。此外，由于医学生将是他们自己的学习对象，这也教会了医学生关于临床研究和研究志愿者是什么样的。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Insulin is a hormone made by the pancrease which lowers blood sugar. Insulin's ability to lower blood sugar is decreased in type 2 diabetes, and also in other conditions including high blood pressure, obesity, and some blood fat disorders. Also, insulin's ability to lower blood sugar is decreased with eating a lot of fat, and is improved with exercise. We are doing this protocol in order to show first year medical students the differences in insulin action with a high fat diet and with exercise. In addition, as medical students will be their own study subjects, this also teaches medical students about clinical research and what being a research volunteer is like.