Quantitative Chemical Biology(RMI)

在后基因组时代，生物医学科学的定量和化学方法正变得越来越重要。通过完成多项测序工作，科学界对自然界的基因‘部分’有了一个全景的看法，现在他们面临着获得这一复杂机械的功能知识的挑战。实现这一目标将需要生物医学研究的创新方法，因此我们的下一代科学家将需要无缝集成定量、化学和生物方法的培训。这个应用程序描述了斯坦福大学创建量化 化学生物学(QCB)计划，这是一个跨校际倡议，将培训跨学科研究的博士后和博士后学生。QCB计划将围绕几个模块进行组织，其中包括跨部门研究生培训计划、QCB研究员计划、专门课程、研讨会和专题讨论会，以及两个支持后基因组研究项目的QCB教职员工指导的设施。这些活动和资源将为培训年轻科学家建立一个新的范例，同时与斯坦福大学目前的项目协同作用，例如多学科研究的Bio-X倡议。 该大学的最终目标是创建一个跨部门的、授予学位的QCB计划。在此期间，该计划将面向被分子药理学和化学系录取并对跨学科研究表现出兴趣的学生，为他们提供不受限制地进入六个学术系的19个QCB附属实验室的机会。QCB计划还将资助与两名或更多QCB附属教员合作的博士后研究员。通过这些机制，QCB培训计划将支持一个多元化的社区，促进跨学科研究和协作发现，为未来的科学家为一个没有边界的科学景观做准备。

Quantitative and chemical approaches to biomedical science are becoming increasingly important in the post-genomic era. Through the completion of multiple sequencing efforts, the scientific community has a panoramic view of nature's genetic 'parts', and it is now challenged with acquiring a functional knowledge of this complex machinery. Achieving this goal will require innovative approaches to biomedical research, and our next generation of scientists will therefore need training that seamlessly integrates quantitative, chemical, and biological methods. This application describes plans by Stanford University to create the Quantitative Chemical Biology (QCB) Program, an interschool initiative that will train predoctoral and postdoctoral students in interdisciplinary research. The QCB Program will be organized around several modules that include an interdepartmental graduate training program, a QCB Fellows program, specialized coursework, seminars and symposia, and two QCB faculty-directed facilities that will support post-genomic research projects. These activities and resources will establish a new paradigm for training young scientists, while synergizing with current programs at Stanford, such as the Bio-X initiative for multidisciplinary research. The University's ultimate goal is the creation of an interdepartmental, degree-granting QCB Program. In the interim, the Program will target students admitted to the Departments of Molecular Pharmacology and Chemistry who demonstrate an interest in interdisciplinary research, providing them with unrestricted access to nineteen QCB-affiliated laboratories in six academic departments. The QCB Program will also sponsor postdoctoral fellows who work collaboratively with two or more QCB-affiliated faculty members. Through these mechanisms, the QCB Training Program will support a diverse community that fosters interdisciplinary research and collaborative discovery, preparing future scientists for a scientific landscape without boundaries.