Clinical Pharmacoepidemiology Training Grant

描述（申请人提供）：宾夕法尼亚大学医学院（SOM）临床流行病学和生物统计学中心（CCEB）与费城科学大学（USP）合作，提出开发临床药物流行病学创新研究培训计划，专门用于培训临床医生严谨，独立的学术研究人员能够使用流行病学中可用的一系列方法来研究药物在人群中的使用和影响。 培训计划的具体目标是：1）提供适用于临床药物流行病学研究的研究技术的深入知识; 2）提供对临床药理学基本原理的理解; 3）提供研究临床药物流行病学相关主题的机会; 4）与临床药物流行病学导师一起提供密集的监督研究经验;和5）通过参加CCEB和USP的系列研讨会，将教师和研究员聚集在一起。受训者将获得临床流行病学硕士学位，并有资格参加临床药理学委员会考试。 为期二至三年的培训计划包括：1）临床流行病学、研究方法学和生物统计学必修课程的核心课程; 2）药物流行病学和药代动力学必修课程; 3）临床药理学的临床经验必修课程; 4）药理学、药学实践或与学员兴趣和经验相关的其他领域的选修课程; 5）广泛的独立阅读; 6）由高级方法学家/临床药物流行病学家，临床药理学家和生物统计学家提供的指导; 7）出席并参与CCEB和USP的研究研讨会;以及8）完成临床药物流行病学的指导独立研究项目。 该计划的优势是：1）CCEB成功的研究培训计划的悠久历史; 2）可供学员使用的全面课程和研究计划; 3）CCEB中国际知名的临床药物流行病学计划; 4）USP提供的杰出药学培训计划; 5）项目负责人和教师的广泛成功培训记录。

DESCRIPTION (provided by applicant): The Center for Clinical Epidemiology and Biostatistics (CCEB) of the University of Pennsylvania School of Medicine (SOM), in collaboration with the University of the Sciences in Philadelphia (USP), proposes to develop an innovative research training program in clinical pharmacoepidemiology, specifically designed to train clinicians to be rigorous, independent academic investigators able to use the range of approaches available in epidemiology to study the use and effects of medications in populations. The specific aims of the training program are to: 1) provide in-depth knowledge of the research techniques appropriate to clinical pharmacoepidemiology research; 2) provide an understanding of the basic principles of clinical pharmacology; 3) provide opportunities for the study of topics related to clinical pharmacoepidemiology; 4) provide intensive, supervised research experience with mentors in clinical pharmacoepidemiology; and 5) bring together faculty and fellows through participation in seminar series in the CCEB and at USP. Trainees would earn a Master's of Science in Clinical Epidemiology (MSCE) degree and be eligible to sit for the Clinical Pharmacology Board exam. The two- to three-year training program consists of: 1) a core curriculum of required courses in clinical epidemiology, research methodology, and biostatistics; 2) required courses in pharmacoepidemiology and pharmacokinetics; 3) required clinical experiences in clinical pharmacology; 4) elective courses in pharmacology, pharmacy practice, or other areas relevant to the trainees' interests and experience; 5) extensive independent readings; 6) mentoring provided by senior methodologists/clinical pharmacoepidemiologists, clinical pharmacologists, and biostatisticians; 7) attendance at and participation in research seminars in the CCEB and at USP; and 8) the completion of a mentored independent research project in clinical pharmacoepidemiology. Strengths of the proposed program are: 1) the long history of successful research training programs in the CCEB; 2) the comprehensive course offerings and research programs that are available to trainees; 3) the internationally renowned clinical pharmacoepidemiology program housed in the CCEB; 4) the distinguished pharmaceutical training program offered by USP; and 5) the extensive successful training records of the program director and faculty.