SCIENTIFIC ANIMATION TOOLS FOR BIOMEDICAL APPLICATIONS

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 国家高分子成像中心(NCMI)寻求与NBCR合作，将NCMI的科学动画和集成库(SAIL)迁移到NBCR的可视化编程环境Vision。 NCMI开发的这些工具已经产生了许多用于各种关键应用的可视化，例如用于评估电子冷冻显微镜在不同细化阶段的三维重建的有效性；在大分子环境中分割蛋白质组分；在提取的分子组分图中发现结构特征，如α螺旋和β片层；制作动画来模拟复杂的生物现象；制作复杂结构的演示动画；生成出版物和演示文稿的图形；帮助合作者了解NCMI的产品；以及提供与同行水平的实验室类似的可视化环境。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The National Center for Macromolecular Imaging (NCMI) seeks to collaborate with NBCR by migrating NCMI's Scientific Animation & Integration Library (SAIL) to NBCR's visual programming environment Vision. These tools developed by NCMI have produced numerous visualizations used in various critical applications such as to evaluate the validity of electron cryomicroscopy 3-D reconstructions at different refinement stages; segmenting protein components in a macromolecular context; discovering structural features such as alpha helices and beta sheets in the extracted molecular component maps; production of animations to model complex biological phenomena; production of animations for presentations of complex structures; generation of graphics for publications and presentations; assisting collaborators in understanding NCMI's products; and providing comparable visualization environments to peer level laboratories.