CLINICAL DIAGNOSIS/BEHAVIORAL ASSESSMENT CORE

临床诊断/行为评估核心（核心C）将负责确保 一套适合年龄的，面试，行为和诊断措施被用于所有项目，雇用 人类实验对象项目2和项目3的目标是高度互补的;因此，它们采用类似的议定书 在青春期后期进行的实验室访视。 作为一项中心活动，核心将由持牌临床医生进行结构化诊断访谈， 参与者群体，从而跟进这些纵向研究中早期做出的诊断， 项目2、3、4和5受益。这些K-SADS面试将使结果被吸收到 关于DSM-IV定义的焦虑症的文献。是否存在临床诊断将 在解决项目2、3、4和5的科学目标方面发挥了重要作用。核心C将支付诊断费用 访问并管理结果数据。 项目2和项目3将对所有样本进行青少年后期行为问题筛查， 以麦克阿瑟健康与行为问卷（HBQ）为主要筛查工具。这些项目将 进行这种筛选，但核心C将以统一的方式管理所得数据并促进分析 跨项目。 特里尔社会压力测试（TSST）在项目2和项目3中都很突出， 所有项目。核心2将促进TSST的统一管理， TSST期间拍摄的录像带。制定和实施一个关于影响和 TSST期间的行为将是核心C的创新贡献。 最后，与我们的顾问Kraemer博士在项目2上，核心将发表关于两个项目的方法论论文。 主题：（1）澄清儿童精神病理学的分类领域诊断与先前 和来自HBQ的并发维度症状评分以及使用受试者操作的其他测量 特征（ROC）曲线逼近。许多发展因素将被纳入其中 分析。(2)检查评估协议中使用的工具的心理测量质量。这些 后一项措施捕捉了青少年焦虑的关键风险因素。

The Clinical Diagnosis/Behavioral Assessment Core (Core C) will be responsible for ensuring that a common set of age appropriate, interview, behavioral, and diagnostic measures are used in all projects that employ human subjects. The aims of Projects 2 and 3 are highly complementary; thus, they employ similar protocols for the laboratory visits done in the late adolescent age period. As a central activity, the core will conduct structured diagnostic interviews by licensed clinicians on select groups of participants, thus following up on diagnoses made earlier in these longitudinal studies and benefiting Projects 2, 3, 4, and 5. These K-SADS interviews will allow results to be assimilated to the literature on anxiety disorders as defined by DSM-IV. The presence or absence of clinical diagnoses will prominently figure into addressing scientific aims on Projects 2, 3, 4, and 5. Core C will pay for diagnostic interviews and manage the resulting data. Projects 2 and 3 will screen their entire samples for behavioral problems in late adolescence, with the MacArthur Health and Behavior Questionnaire (HBQ) as the main screening instrument. The projects will conduct this screening, but Core C will manage the resulting data in a uniform manner and facilitate analyses across projects. The Trier Social Stress Test (TSST) figures prominently in both Project 2 and 3, and relates conceptually to all projects. Core 2 will facilitate uniform administration of the TSST and conduct behavioral coding of videotapes taken during the TSST. The development and implementation of a coding scheme for affect and behavior during the TSST will be an innovative contribution of Core C. Finally, with our consultant Dr. Kraemer on Project 2, the Core will publish methodological papers on two topics: (1) Clarifying the relationship between categorical field diagnoses of child psychopathology and prior and concurrent dimensional symptom scores from the HBQ and other measures using Receiver Operating Characteristic (ROC) curve approaches. Many developmental factors will be incorporated into these analyses. (2) Examining the psychometric quality of instruments used in the assessment protocols. These latter measures capture key risk factors for adolescent anxiety.