LONGITUDINAL T1? MRI OF ADULTS WITH CHONDROMALACIA FOLLOWING ARTHROSCOPY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 先前已经证明，T1？松弛速率的升高与病灶 关节镜检查证实为软骨软化症的软骨损伤。它还没有显示出是什么 在关节镜检查、去毛刺和软骨成形术过程中发生的影响，如果有的话，发挥作用 在随后的软骨修复或退变中。目的：确定手术后的疗效。 在这些过程中，将进行纵向T1？MRI来跟踪软骨的任何后续变化 正直和健康。这项研究将跟踪以下软骨健康的进展 分别于术后3个月和9个月行关节镜手术。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. It is has been previously demonstrated that an elevated T1¿ relaxation rate correlates with focal cartilage lesions from arthroscopically confirmed chondromalacia. It has yet to be shown what effects, if any, procedures that occur during this arthroscopy, deburring and chondroplasty, play in either subsequent cartilage repair or degeneration. To determine the post-surgical effects of these procedures, longitudinal T1¿ MRI will occur to track any subsequent changes of cartilage integrity and health. This study will track the progression of cartilage health following these arthroscopic procedures using T1¿ MRI at 3 and 9 months post-surgery.