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N- & O-GLYCANS OF RECOMBINANT HUMAN OVIDUCTAL GLYCOPROTEIN EXPRESSED IN HEK293

N- & O-GLYCANS OF RECOMBINANT HUMAN OVIDUCTAL GLYCOPROTEIN EXPRESSED IN HEK293
N-
批准号:
8363118
负责人:
RON ORLANDO
金额:
$0.34万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2011
资助国家:
美国
项目状态:
已结题
起止时间:
2011-06-01 至 2012-05-31

项目摘要

项目成果

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中文摘要
翻译
这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的, 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量, 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 输卵管特异性糖蛋白,又称输卵管蛋白或MUC9,是由哺乳动物输卵管非纤毛分泌细胞合成和分泌的一种主要的粘蛋白样糖蛋白。输卵管特异性糖蛋白在迄今研究过的所有物种中都是保守的,包括人类。骨钙素的合成和分泌受到雌激素的控制。体外功能研究表明,OGP在受精和早期胚胎发育过程中发挥重要作用。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Oviduct-specific glycoprotein (OGP), also known as oviductin or MUC9, is a major mucin-like glycoprotein synthesized and secreted by non-ciliated secretory cells of mammalian oviducts. Oviduct-specific glycoprotein is conserved among all species examined to date including humans. The synthesis and secretion of OGP are under estrogen control. In vitro functional studies showed that OGP plays important roles during fertilization and early embryo development.
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Isotopically Labeled Heparan Sulfate Glycosaminoglycan Disaccharides for use as Internal Standards
  • 批准号:
    10080563
  • 项目类别:
  • 资助金额:
    $25.21万
  • 财政年份:
    2020
  • 负责人:
    RON ORLANDO
  • 依托单位:
CREATING ANTIBODIES TO ENABLE THE STUDY OF MYCOBACTERIUM TUBERCULOSIS INFECTIONS IN GUINEA PIGS
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    10027950
  • 项目类别:
  • 资助金额:
    $65.32万
  • 财政年份:
    2019
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    RON ORLANDO
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Generation of antibodies to monitor Notch O-fucosylation in vivo
  • 批准号:
    9200115
  • 项目类别:
  • 资助金额:
    $24.23万
  • 财政年份:
    2016
  • 负责人:
    RON ORLANDO
  • 依托单位:
Development of Isotopically Labeled Glycoproteins for use as Internal Standards
  • 批准号:
    9908593
  • 项目类别:
  • 资助金额:
    $35.26万
  • 财政年份:
    2015
  • 负责人:
    RON ORLANDO
  • 依托单位:
海外基金