Research Training in Gastroenterology

请参阅说明)： 这是一份与之竞争的续订胃肠病学培训计划的申请 第一次资助是在1999年。从那时起，20名受训人员得到了支持，其中除4人外，其余都是全职 学术职位，或全职从事工业研究，或仍在培训中。该计划的目标是提供 为致力于调查职业生涯的年轻研究人员提供两三年的研究培训 胃肠病学或相关领域。研究培训的类型包括基础、转化型或临床型 研究，或这些的组合。受训人员可能是医学博士、医学博士或已完成临床或 正在接受研究生培训，并正在寻求进一步的胃肠学研究培训。培训将主要包括 有指导的研究，将提供紧张的实践体验。内容丰富的教学课程菜单， 还将举办讲习班、研讨会和会议。以患者为中心的研究的实习生将 预期完成课程作业和论文要求，以获得MMS、公共卫生硕士或同等学位。全 受训者将提交K系列NIH奖项或研究支持的拨款申请 基础在第三年的研究培训。 学员将由具有广泛兴趣和专业知识的经验丰富的研究导师指导。 从基础细胞和分子生物学到临床研究。由凯利博士组成的培训委员会， 罗布森、特霍斯特和兰特以及其他一两名培训人员将监督整个研究培训 计划，选择合适的候选人并监测进展情况。实习生研究计划将在#年提供 与该司的临床卓越中心相结合的四个广泛领域：1.肠道感染 和豁免权2)肝损伤和纤维化3.)维管生物学和4.)上皮生物学。培训 该计划将利用GL司内优秀的GL研究基地， 医学和外科以及哈佛医学院和公共卫生学院。培训计划将 还受益于BIDMC组织良好、资金充足的综合临床研究中心， 以及邻近的两个消化疾病中心，一个在哈佛医学院，一个在 第二位是马萨诸塞州综合医院。后勤司在招聘女性方面有良好的记录。 以及少数族裔受训人员和教职员工，并为今后的少数族裔外联和招聘制定了积极的计划。 相关性(请参阅说明)： 这一计划将解决一般医学特别是胃肠病学中的一个关键问题： 训练有素的内科科学家和基础研究人员越来越少，他们专注于Gl和肝病。 该计划将把BASE研究与临床问题结合起来，以更好地解决 在我们的专业中，诊断和治疗方面的信息差距。我们的最终目标是培养出 能够成功地竞争初创研究资金和初级教师职位，以及谁 继续表现出对基础或临床研究的实质性承诺。

See instructions): This is a competing continuation application for renewal of a training program in gastroenterology that was first funded in 1999. Since then, 20 trainees have been supported, of whom all but four are in full time academic positions, or full-time research in industry, or still in training. The goal of this program is to provide two or three years of research training for young researchers committed to a career in investigative gastroenterology or allied fields. The types of research training include basic, translational or clinical research, or combinations of these. Trainees may be MDs, MD-PhDs or PhDs who have finished clinical or graduate training and are seeking further research training in gastroenterology. Training will consist primarily of mentored research that will provide intense hands-on experience. An extensive menu of didactic courses, workshops, seminars and conferences will also be provided. Trainees in patient-oriented research will be expected to complete course work and thesis requirements to obtain an MMS, MPH or equivalent degree. All trainees will be expected to submit grant applications for K-series NIH awards or support from research foundations during the 3rd year of research training. Trainees will be supervised by experienced research mentors with a wide range of interests and expertise from basic cellular and molecular biology to clinical research. A training committee composed of Drs. Kelly, Robson, Terhorst and Lament and one or two other training faculty will monitor the overall research training program, select suitable candidates and monitor progress. Trainee research programs will be available in four broad areas that are integrated with clinical centers of excellence in the Division: 1.) Intestinal Infection and Immunity 2.) Liver Injury and Fibrosis 3.) Vascular Biology and 4.) Epithelial Biology. The training program will take advantage of the outstanding Gl research base within the Gl Division, the Departments of Medicine and Surgery and at harvard Medical School and School of Public Health. The training program will also benefit from the availability of a well organized and funded General Clinical Research Center at BIDMC, as well as the close proximity of two Digestive Disease Centers, one at Harvard Medical School and a second at Massachusetts General Hospital. The Gl Division has a good track record of recruitment of female and minority trainees and faculty, and has an active plan for future minority outreach and recruitment. RELEVANCE (See instructions): This program will address a critical issue in medicine in general and gastroenterology in particular: the dwindling supply of well-trained physician-scientists and basic researchers focused on Gl and liver diseases. The program will integrate bench research with clinical questions and problems to better address the information gaps in diagnosis and treatment in our specialty. Our ultimate goal is to produce individuals who are able to compete successfully for start-up research funding and for entry level faculty positions and who continue to exhibit a substantial commitment to basic or clinical research.