Interaction between Moz and PRC1 in defining epigenetic states and gene expression patterns
Interaction between Moz and PRC1 in defining epigenetic states and gene expression patterns
批准号:
nhmrc : 1008699
负责人:
A/Pr Anne Voss
金额:
$28.49万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2013-12-31
中文摘要
基因表达调控涉及所有疾病过程。基因的异常表达与肿瘤的形成尤其相关。在这个项目中,我们确定了致癌基因MOZ和另一个致癌基因BMI1之间的关系。这些蛋白质共同调节染色质结构水平上控制基因表达的最重要的系统之一。
英文摘要
Regulation of gene expression is implicated in all disease processes. Aberrant gene expression is particularly associated with tumour formation. In this project we determine the relationship between an oncogene MOZ and another oncogene BMI1. Together these proteins regulate one of the most important systems controlling gene expression at the level of chromatin structure.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
The molecular and biological roles of growth inhibiting chromatin binding proteins
-
批准号:nhmrc : GNT1143612
-
项目类别:Project Grants
-
资助金额:$81.48万
-
财政年份:2018
-
负责人:A/Pr Anne Voss
-
依托单位:
The molecular and biological roles of growth inhibiting chromatin binding proteins
-
批准号:nhmrc : 1143612
-
项目类别:Project Grants
-
资助金额:$55.09万
-
财政年份:2018
-
负责人:A/Pr Anne Voss
-
依托单位:
Regulation of haematopoietic stem cells through histone modifications
-
批准号:nhmrc : 1084248
-
项目类别:Project Grants
-
资助金额:$53.14万
-
财政年份:2015
-
负责人:A/Pr Anne Voss
-
依托单位:
Chromatin regulation of neural stem cell multipotency
-
批准号:nhmrc : 1084352
-
项目类别:Project Grants
-
资助金额:$50.42万
-
财政年份:2015
-
负责人:A/Pr Anne Voss
-
依托单位:
TAF8 is a suppressor of cell death
-
批准号:nhmrc : 1084504
-
项目类别:Project Grants
-
资助金额:$38.04万
-
财政年份:2015
-
负责人:A/Pr Anne Voss
-
依托单位:
NHMRC Research Fellowship
-
批准号:nhmrc : GNT1081421
-
项目类别:Research Fellowships
-
资助金额:$61.16万
-
财政年份:2015
-
负责人:A/Pr Anne Voss
-
依托单位:
MOZ regulates cellular senescence
-
批准号:nhmrc : 1084509
-
项目类别:Project Grants
-
资助金额:$33.24万
-
财政年份:2015
-
负责人:A/Pr Anne Voss
-
依托单位:
TAF8 is a suppressor of cell death
-
批准号:nhmrc : GNT1084504
-
项目类别:Project Grants
-
资助金额:$55.26万
-
财政年份:2015
-
负责人:A/Pr Anne Voss
-
依托单位:
NHMRC Research Fellowship
-
批准号:nhmrc : 1081421
-
项目类别:Research Fellowships
-
资助金额:$42.58万
-
财政年份:2015
-
负责人:A/Pr Anne Voss
-
依托单位:
Understanding the regulation of craniofacial development through control of chromatin and gene transcription
-
批准号:nhmrc : 1051078
-
项目类别:Project Grants
-
资助金额:$41.1万
-
财政年份:2013
-
负责人:A/Pr Anne Voss
-
依托单位:
The role of Moz, an epigenetic regulator, in the pathogenesis of leukaemia
-
批准号:nhmrc : 1030704
-
项目类别:Project Grants
-
资助金额:$47.6万
-
财政年份:2012
-
负责人:A/Pr Anne Voss
-
依托单位:
Understanding the control of brain development and endocrine function through central regulation of gene transcription
-
批准号:nhmrc : 1029481
-
项目类别:Project Grants
-
资助金额:$41.66万
-
财政年份:2012
-
负责人:A/Pr Anne Voss
-
依托单位:
Effects of the histone acetyltransferases MOZ and QKF on chromatin modifications
-
批准号:nhmrc : 1010851
-
项目类别:Project Grants
-
资助金额:$23.31万
-
财政年份:2011
-
负责人:A/Pr Anne Voss
-
依托单位:
The role of the suppressors of cytokine signalling 6 and 7 in cerebral cortex development
-
批准号:nhmrc : 637346
-
项目类别:NHMRC Project Grants
-
资助金额:$25.15万
-
财政年份:2010
-
负责人:A/Pr Anne Voss
-
依托单位:
The role of the transcriptional co-activator, Qkf, in adult neural stem cell self-renewal and multi-potency.
-
批准号:nhmrc : 575557
-
项目类别:NHMRC Project Grants
-
资助金额:$26.92万
-
财政年份:2009
-
负责人:A/Pr Anne Voss
-
依托单位:
Uncoupled Research Fellowship
-
批准号:nhmrc : 575512
-
项目类别:NHMRC Research Fellowships
-
资助金额:$46.88万
-
财政年份:2009
-
负责人:A/Pr Anne Voss
-
依托单位:
The role of the Ras signalling molecule, C3G, in the interaction of neural precursor cells and their environment
-
批准号:nhmrc : 461215
-
项目类别:NHMRC Project Grants
-
资助金额:$21.3万
-
财政年份:2007
-
负责人:A/Pr Anne Voss
-
依托单位:
Body segment identity specification by the transcription regulator, Moz
-
批准号:nhmrc : 461216
-
项目类别:NHMRC Project Grants
-
资助金额:$24.43万
-
财政年份:2007
-
负责人:A/Pr Anne Voss
-
依托单位:
The role of the MYST family transcriptional co-activator, Mof, in embryonic development
-
批准号:nhmrc : 461218
-
项目类别:NHMRC Project Grants
-
资助金额:$21.3万
-
财政年份:2007
-
负责人:A/Pr Anne Voss
-
依托单位:
The role of MOZ in the development of the hematopoietic system, spleen and thymus
-
批准号:nhmrc : 356228
-
项目类别:NHMRC Project Grants
-
资助金额:$21.63万
-
财政年份:2005
-
负责人:A/Pr Anne Voss
-
依托单位:
海外基金