2015 Collagen Gordon Research Conference and Gordon Research Seminar

 描述(由申请人提供)：这是2015年胶原蛋白戈登研究会议(GRC)和相关的戈登研究研讨会(GRS)的部分支持申请。这将是GRC自1970年成立以来的第27次会议，以及自2011年成立以来的第3次会议。GRC将于7月12日至7月17日在新伦敦的科尔比-索耶学院举行。在此之前，将于7月11日至7月12日在同一地点举行GRS。从历史上看，GRC为初级和高级科学家组成的多样化的国际小组提供了一个独特的论坛，介绍和讨论结缔组织化学、生物学和病理学前沿的最新进展，重点放在胶原蛋白上，胶原蛋白是这些组织的主要组成部分。会议提供了一个有利于不同兴趣和技术专长的研究人员之间进行非正式互动和讨论的环境，以丰富和推进该领域。合作建立了，新的科学家被招募到这个领域，关于胶原蛋白的重大发现经常在这次会议上首次报道。GRS为研究生和博士后研究员提供了一个论坛，在同行和导师中展示和讨论他们的工作。鼓励所有GRS与会者参加GRC，提高了青年科学家的参与度，丰富了会议氛围。2015年胶原GRC和GRS的具体目标是：1)交流和传播新的、主要是未发表的数据和概念；2)促进基础、临床和行业研究人员之间的互动和合作；3)促进学生和同事之间的互动以及与知名科学家的互动；以及4)增加多样性并吸引新的研究人员进入胶原蛋白领域。该计划将侧重于与胶原蛋白的表达、生物合成和结构与其功能和病理学有关的新的、未发表的发现和概念，特别是在发育生物学和肌肉、骨骼、软骨、韧带、肌腱和皮肤的疾病以及炎症和风湿性疾病方面的应用。重要的是，新的会议主题已经被整合到传统的计划中，以增强人们的兴趣，增加对会议的参与，确保整个星期的热情，并促进该领域的重大进展。每节课都将有研究生和博士后研究员从GRS中挑选出来。与前一次会议相关的新主题包括基底膜中的胶原素、细胞壁龛中的胶原素和细胞信号、生物生理学中的胶原素以及基于胶原蛋白的材料和生物工程。另一场会议将就胶原基因和基因网络的表达和调控、胶原分子中不同结构域的结构和功能、胶原蛋白稳态和病理学中的胶原蛋白等重要主题提供最新进展。总体而言，这次国际会议将展示胶原蛋白研究领域的主要进展，并将一如既往地成为该领域的开创性会议。

 DESCRIPTION (provided by applicant): This is an application for partial support of the 2015 Collagen Gordon Research Conference (GRC) and the associated Gordon Research Seminar (GRS). It will be the 27th meeting of this GRC since its inception in 1970 and 3rd meeting of the GRS since its inception in 2011. The GRC will be held at the Colby-Sawyer College in New London, NH, from July 12th to July 17th. It will be preceded by the GRS at the same location, from July 11th to July 12th. This GRC has historically provided a unique forum for a diverse, international group of junior and senior scientists to present and discuss recent advances at the frontier of chemistry, biology and pathology of connective tissues with a focus on collagens, which are the major components of these tissues. The conference provides an environment conducive to informal interactions and discussions among investigators of different interests and technical expertise that enrich and advance the field. Collaborations are established, new scientists are recruited to the field, and major discoveries about collagen are often reported for the first time at this conference. The GRS provides a forum for graduate students and postdoctoral fellows to showcase and discuss their work among peers and mentors. All GRS attendees are encouraged to participate in the GRC, enhancing the participation of young scientists and enriching the conference atmosphere. The specific aims of the 2015 Collagen GRC and GRS are: 1) to communicate and disseminate new, mostly unpublished data and concepts; 2) to promote interactions and collaborations among basic, clinical, and industry researchers; 3) to facilitate student and fellow interactions among each other and with established scientists; and 4) to increase diversity and attract new researchers to the collagen field. The program will focus on new, unpublished findings and concepts relating expression, biosynthesis and structure of collagens to their function and pathology, particularly in applicatio to developmental biology and disorders of muscle, bone, cartilage, ligaments, tendons, and skin as well as to inflammation and rheumatic diseases. Importantly, new session topics have been integrated into the traditional program to bolster interest, increase participation in the conference, ensure enthusiasm throughout the week, and promote major advancements in the field. Each session will feature graduate students and postdoctoral fellows selected from the GRS. New topics relative to the previous conference include Collagens in Basement Membranes, Collagens in Cell Niche and Cell Signaling, Collagens in Organism Physiology, and Collagen Based Materials and Bioengineering. The other session will provide updates on such important topics as Expression and Regulation of Collagen Genes and Gene Networks, Structure and Function of Different Domains in Collagen Molecules, Collagen Homeostasis, and Collagens in Pathology. Overall this international conference will showcase the major advances in the field of collagen research and will be, as it has always been, the seminal conference in the field.