2011 CSHL Yeast Cell Biology Conference

描述（由申请人提供）：过去十年的研究促使我们在理解细胞功能的分子机制方面取得了巨大进展。进步来自多种细胞类型和生物体。值得注意的是，酵母系统通常处于发现新蛋白质、途径、结构和机械见解的最前沿。尽管酵母是一种单细胞生物，但它的研究也揭示了对多细胞生物生理学和专门组织功能的意想不到的见解。酵母细胞生物学仍然是一个充满活力的研究领域，酵母系统作为新概念和新技术的试验平台，对更大的研究界至关重要。酵母细胞生物学系列会议（2011年，2013年和2015年）的智力价值在于，它将为讨论和交流有关真核细胞内部功能的前沿发现创造一个首要论坛。该计划将包括八个会议，涵盖细胞生物学的广泛主题，包括膜运输，细胞骨架，细胞周期，极性，染色体，核组织和信号，重点是整合这些不同事件的高阶调控。每次会议将由相关领域的两名杰出和知名调查员主持。除了会议主席提出的简短演讲外，所有演讲和海报都将从提交的摘要中选出，大部分演讲将由学生，博士后研究员和其他初级研究人员提供。预计将有超过275名科学家参加。其中，一半以上可能是研究生和博士后研究员。会议将为细胞生物学知识前沿的一些最令人兴奋的数据和概念的自由流动的讨论提供一个刺激的环境。鉴于该领域的快速发展，本次会议为与会者提供了一个令人兴奋的机会，了解与他们自己在酵母和其他系统中的研究相关的最新突破。拟议活动的广泛影响是多方面的。首先，它们包括对酵母细胞生物学以外其他领域的科学影响，因为这一领域的发现将继续促进影响所有生命形式生理学的基础发现和见解的快速发展。其次，它们还包括教育、培训、资源共享以及互动和合作机会等要素。特别是，会议将提供：㈠为年轻科学家提供培训机会，以促进发展演讲技巧以及全面的科学素质和分析严谨性; ㈡提供一个亲密的环境，以促进所有职业层次的科学家之间有意义的科学互动; ㈢在研究和教育机构的多个层次之间传播知识;（iv）分享物质和信息资源;（v）提供开展合作的机会，这可使来自小型实验室和/或主要来自本科（教学）机构的科学家受益，他们的资源可能比来自大型研究机构的科学家少，接触尖端技术的机会也更有限。

DESCRIPTION (provided by applicant): Research in the past decade has spurred tremendous progress in our understanding of molecular mechanisms that underlie cell function. Advances have come from multiple cell types and organisms. Notably, yeast systems often have been at the forefront in the discovery of new proteins, pathways, structures, and in mechanistic insights. Despite its existence as a unicellular organism, yeast research has also revealed unexpected insights into the physiology of multicellular organisms and the functions of specialized tissues. Yeast cell biology continues to be a vibrant field of research, and yeast systems are critically important to the larger research community by serving as the test bed for new concepts and technologies. The intellectual merit of the meeting series on Yeast Cell Biology (2011, 2013 and 2015) is that it will create a premier forum for the discussion and exchange of cutting-edge discoveries about the internal functions of eukaryotic cells. The program will include eight sessions covering a wide range of topics in cell biology including membrane trafficking, cytoskeleton, the cell cycle, polarity, chromosomes, nuclear organization, and signaling, with a focus on higher order regulation that integrates these diverse events. Each session will be led by two outstanding and well-known investigators in the relevant area. With the exception of short talks presented by the session chairs, all of the talks and posters to be presented will be selected from submitted abstracts, and most of the talks will be given by students, postdoctoral fellows and other junior investigators. It is expected that more than 275 scientists will attend. Of these, over half are likely to be graduate students and postdoctoral fellows. The meeting will serve to provide a stimulating environment for the free flowing discussion of some of the most exciting data and concepts at the frontiers of knowledge in cell biology. Given the rapid pace of developments in the field, this meeting presents an exciting opportunity for participants to learn about recent breakthroughs that will be relevant to their own research both in yeast and in other systems. The broader impacts of the proposed activity are manifold. First, they include the scientific implications for other fields beyond yeast cell biology, as discoveries in this field will continue to foster a rapid pace of fundamental discoveries and insights that impact the physiologies of all life forms. Second, they also include elements of education, training, resource sharing, and opportunities for interaction and collaboration. In particular, the meeting will provide: (i) training opportunities for junior scientists that will promote the development of presentation skills as well as overall scientific quality and analytical rigor; (ii) an intimate setting that will foster meaningful scientific interactions among scientists at all career levels; (iii) the dissemination of knowledge among multiple strata of research and educational institutions; (iv) sharing of resources, both material and informational; and (v) opportunities for the initiation of collaborations, which can benefit scientists from smaller labs and/or from primarily undergraduate (teaching) institutions who may have fewer resources and more limited access to cutting-edge technologies than do scientists from major research institutions.