Investigation of the proinflammatory function of platelets during ischaemia-reperfusion injury
Investigation of the proinflammatory function of platelets during ischaemia-reperfusion injury
批准号:
nhmrc : 1048574
负责人:
Prof Shaun Jackson
金额:
$36.86万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2013
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2013-01-01 至 2015-12-31
中文摘要
血小板是重要的止血血细胞。血小板还通过调节白细胞的功能来调节炎症。血小板对白细胞的过度刺激可能会导致与多种心血管疾病相关的组织损伤,包括心脏病和中风。这项拨款申请旨在研究血小板在心脏病发作或中风期间促进炎症的确切机制。
英文摘要
Platelets are important blood cells that stop bleeding. Platelets also regulate inflammation by modulating the function of white blood cells. Excessive stimulation of white cells by platelets may cause tissue damage relevant to a broad of cardiovascular diseases, including heart disease and stroke. This grant application aims to investigate the precise mechanism by which platelets promote inflammation during a heart attack or stroke.
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会议论文
Identification of a new thrombosis mechanism triggered by dying platelets
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批准号:nhmrc : 1127278
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项目类别:Project Grants
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资助金额:$41.54万
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财政年份:2017
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负责人:Prof Shaun Jackson
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依托单位:
Identification of a new thrombosis mechanism triggered by dying platelets
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批准号:nhmrc : GNT1127278
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项目类别:Project Grants
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资助金额:$60.87万
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财政年份:2017
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负责人:Prof Shaun Jackson
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依托单位:
Intravascular leukocyte trafficking during thromboinflammation
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批准号:nhmrc : 1127267
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项目类别:Project Grants
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资助金额:$45.64万
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财政年份:2017
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负责人:Prof Shaun Jackson
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依托单位:
Investigating a potential new treatment for stroke
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批准号:nhmrc : 1079400
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项目类别:Research Fellowships
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资助金额:$58.58万
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财政年份:2015
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负责人:Prof Shaun Jackson
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依托单位:
Investigating a potential new treatment for stroke
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批准号:nhmrc : GNT1079400
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项目类别:Research Fellowships
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资助金额:$83.69万
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财政年份:2015
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负责人:Prof Shaun Jackson
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依托单位:
Identification of a novel adhesion mechanism regulating platelet-endothelial interactions.
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批准号:nhmrc : 1066957
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项目类别:Project Grants
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资助金额:$33.45万
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财政年份:2014
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负责人:Prof Shaun Jackson
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依托单位:
Development of an ultra-high speed spinning disk confocal micro-particle image velocimetry (PIV) platform for the investigation of cardiovascular disease
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批准号:LE120100043
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项目类别:Linkage Infrastructure, Equipment and Facilities
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资助金额:$22.0万
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财政年份:2014
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负责人:Prof Shaun Jackson
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依托单位:
Investigation of a novel mechanism causing platelet hyperactivity in diabetes
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批准号:nhmrc : 1042886
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项目类别:Project Grants
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资助金额:$38.88万
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财政年份:2013
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负责人:Prof Shaun Jackson
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依托单位:
Investigation of a New Leukocyte Recruitment Mechanism at Sites of Vascular Injury
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批准号:nhmrc : 1028564
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项目类别:Project Grants
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资助金额:$36.49万
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财政年份:2012
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负责人:Prof Shaun Jackson
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依托单位:
Australia Fellowship
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批准号:nhmrc : 606718
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项目类别:NHMRC Research Fellowships
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资助金额:$266.72万
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财政年份:2010
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负责人:Prof Shaun Jackson
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依托单位:
Development of Model Systems to Investigate Blood Hydrodynamic Parameters Affecting Blood Cell Function: An Interdisciplinary Approach
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批准号:DP0987643
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项目类别:Discovery Projects
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资助金额:$20.72万
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财政年份:2009
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负责人:Prof Shaun Jackson
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依托单位:
Uncoupled Research Fellowship
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批准号:nhmrc : 545953
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项目类别:NHMRC Research Fellowships
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资助金额:$12.82万
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财政年份:2009
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负责人:Prof Shaun Jackson
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依托单位:
Investigation of the role for GPVI in platelet function and thrombosis
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批准号:nhmrc : 491166
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项目类别:NHMRC Project Grants
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资助金额:$36.19万
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财政年份:2008
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负责人:Prof Shaun Jackson
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依托单位:
Investigate novel functional roles for PI 3-kinases in platelets.
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批准号:nhmrc : 491165
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项目类别:NHMRC Project Grants
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资助金额:$35.82万
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财政年份:2008
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负责人:Prof Shaun Jackson
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依托单位:
Examination of the Calcium Signalling Dynamics Linked to Integrin Adhesion Utilising a Novel Micro-imaging System
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批准号:DP0663904
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项目类别:Discovery Projects
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资助金额:$20.34万
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财政年份:2006
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负责人:Prof Shaun Jackson
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依托单位:
Investigate the role of PAF and CD40 ligand in regulating the proinflammatory properties of platelets
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批准号:nhmrc : 384249
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项目类别:NHMRC Project Grants
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资助金额:$33.82万
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财政年份:2006
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负责人:Prof Shaun Jackson
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依托单位:
Investigation of a novel role for Factor XIII in regulating the adhesive function of platelets
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批准号:nhmrc : 334080
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项目类别:NHMRC Project Grants
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资助金额:$16.2万
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财政年份:2005
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负责人:Prof Shaun Jackson
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依托单位:
Investigation of mechanotransduction mechanisms in platelets
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批准号:nhmrc : 284266
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项目类别:NHMRC Project Grants
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资助金额:$32.11万
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财政年份:2004
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负责人:Prof Shaun Jackson
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依托单位:
Uncoupled Research Fellowship
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批准号:nhmrc : 284267
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项目类别:NHMRC Research Fellowships
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资助金额:$47.59万
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财政年份:2004
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负责人:Prof Shaun Jackson
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依托单位:
Investigation of Activating signals Transmitted during Platelet Aggregation
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批准号:nhmrc : 237011
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项目类别:NHMRC Project Grants
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资助金额:$17.85万
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财政年份:2003
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负责人:Prof Shaun Jackson
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依托单位:
海外基金