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Conduct of studies to evaluate the toxic and carcinogenic potential of sulfolane in laboratory animals for the National Toxicology Program (NTP)

Conduct of studies to evaluate the toxic and carcinogenic potential of sulfolane in laboratory animals for the National Toxicology Program (NTP)
为国家毒理学计划 (NTP) 开展研究,评估环丁砜对实验动物的毒性和致癌潜力
批准号:
9162301
负责人:
MILTON D HEJTMANCIK
金额:
$252.62万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2014
资助国家:
美国
项目状态:
已结题
起止时间:
2014-04-15 至 2015-04-14

项目摘要

项目成果

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中文摘要
翻译
本项目的目的是评估大鼠和小鼠在饮用水中暴露后的慢性毒性和致癌性。人们对接触受污染的地下水(特别是在阿拉斯加)后产生的潜在毒性感到担忧。对硫代烷进行的为期2年的慢性毒性和致癌性研究正在进行中。这些研究包括发育标志、亚慢性毒性和免疫毒性的评估。
英文摘要
The goal of this project is to evaluate the chronic toxicity and carcinogenicity of sulfolane in rats and mice, following exposure in drinking water. There are concerns over the potential toxicity of sulfolane following exposure in contaminated ground water, particularly in Alaska. 2-Year chronic toxicity and carcinogenicity studies of sulfolane are in the in life phase. These studies include an assessment of developmental landmarks, subchronic toxicity and immunotoxicity. Keywords: toxicity, carcinogenicity, drinking water, sulfolane
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toxic and potential of vanadyl sulfate and sodium metavanadate in laboratory animals for the National Toxicology Program (NTP)
  • 批准号:
    8948076
  • 项目类别:
  • 资助金额:
    $81.42万
  • 财政年份:
    2014
  • 负责人:
    MILTON D HEJTMANCIK
  • 依托单位:
Conduct of studies to evaluate the toxic and carcinogenic potential of naturally occurring asbestos in laboratory animals for the National Toxicology Program (NTP)
  • 批准号:
    9162302
  • 项目类别:
  • 资助金额:
    $100.0万
  • 财政年份:
    2014
  • 负责人:
    MILTON D HEJTMANCIK
  • 依托单位:
Conduct of studies to evaluate the toxic and potential of vanadyl sulfate and sodium metavanadate in laboratory animals for the National Toxicology Program (NTP)
  • 批准号:
    9162299
  • 项目类别:
  • 资助金额:
    $100.0万
  • 财政年份:
    2014
  • 负责人:
    MILTON D HEJTMANCIK
  • 依托单位:
toxic and carcinogenic potential of alpha-pinene in laboratory animals for the National Toxicology Program (NTP)
  • 批准号:
    8948077
  • 项目类别:
  • 资助金额:
    $107.83万
  • 财政年份:
    2014
  • 负责人:
    MILTON D HEJTMANCIK
  • 依托单位:
海外基金