Vanderbilt Training Program in Molecular and Genetic Epidemiology of Cancer

描述（申请人提供）：分子生物学和遗传学技术和知识的快速发展和进步导致了癌症病因学研究的重大突破。虽然癌症流行病学领域正在迅速走向一个跨学科和多学科合作研究是中心主题的新时代，但在流行病学，分子生物学和遗传学的界面上工作的科学家严重短缺。我们建议建立范德比尔特癌症分子和遗传流行病学培训计划（Vanderbilt-MAGEC），为来自不同学科的博士后研究员提供方法学工具，实用的实验室和调查研究知识，以及开展癌症分子和遗传流行病学独立职业所需的实践研究和授予写作经验。 范德比尔特MAGEC的具体目标是：（1）招募具有流行病学，遗传学和/或生物学背景的特殊，种族多样化的候选人（2名MD和5名博士）。候选人将在当地和全国范围内从最近完成相关科学（特别是流行病学，遗传学，生物学，化学，生物统计学）博士学位或对癌症流行病学研究感兴趣的医学博士中招募。(2)开发和提供个性化的教学培训，以补充每个受训者之前的培训背景，并沿着他们期望的职业道路（癌症的分子或遗传流行病学）。具体培训将包括课程、研讨会、工作室和期刊俱乐部。(3)为每一位学员建立一个多学科的导师团队， 研究人员还将培训学员纳入国家癌症研究所资助的癌症流行病学研究项目。(4)通过跟踪短期和长期结果来评估范德比尔特-MAGEC的影响。所有学员的预期短期成果包括在高影响力的同行评审期刊上发表论文，并向内部或外部资助机构提交NIH质量的赠款提案。长期成果将包括癌症研究职业安置和NIH赠款资金。该计划建立在优秀的研究和教育培训环境，优秀的研究人员和教育工作者，多个正在进行的尖端研究项目，特殊的数据/生物标本和人口资源，以及范德比尔特跨学科培训的丰富历史基础上，具有出色的基础设施和教师，以创建癌症分子和遗传流行病学的示范性培训计划。

DESCRIPTION (provided by applicant): The rapid development and advancement of technologies and knowledge in molecular biology and genetics have led to major breakthroughs in cancer etiology research. While the field of cancer epidemiology is moving rapidly toward a new era where interdisciplinary and multidisciplinary collaborative research is the central theme, there is a severe shortage of scientists working at the interfaces of the epidemiology, molecular biology, and genetics. We propose to establish the Vanderbilt Training Program in Molecular and Genetic Epidemiology of Cancer (Vanderbilt-MAGEC) to equip postdoctoral fellows from a variety of disciplines with the methodological tools, practical laboratory and survey-research knowledge, and hands-on research and grant writing experience necessary to launch an independent career in the molecular and genetic epidemiology of cancer. The specific aims of the Vanderbilt MAGEC are: (1) To recruit exceptional, ethnically diverse candidates (2 MD and 5 PhD) with strong backgrounds in epidemiology, genetics, and/or biology. Candidates will be recruited locally and nationally from among persons who have recently completed PhD degrees in relevant sciences (particularly epidemiology, genetics, biology, chemistry, biostatistics) or MDs with serious interests in cancer epidemiology research. (2) To develop and deliver individualized didactic training tailored to complement each trainee's prior training background and launch them along their desired career paths (molecular or genetic epidemiology of cancer). Specific training will consist of courses, seminars, studios, and a journal club. (3) To establish a multidisciplinary mentor team for each trainee and integrate all trainees into NCI-funded cancer epidemiology research projects. (4) To evaluate the impact of the Vanderbilt-MAGEC by tracking short- and long-term outcomes. Expected short-term outcomes for all trainees include publishing papers in high-impact, peer-reviewed journals and submitting an NIH-quality grant proposal to an internal or external funding agency. Long-term outcomes will include cancer research career placements and NIH grant funding. This program, built upon an outstanding research and education training environment, an excellent body of researchers and educators, multiple, ongoing, cutting-edge research projects, exceptional data/biospecimen and population resources, and the rich history of interdisciplinary training at Vanderbilt, has an outstanding infrastructure and faculty to create an exemplary training program in the molecular and genetic epidemiology of cancer.