Surgery Research Training Program

项目摘要/摘要 这项拟议的新博士后培训计划的重点是培养临床医生和科学家，主要是 外科医生和外科实习生，在组成翻译领域的技术和方法方面 研究和系统生物学。每个实习生将与一名研究导师和一名职业导师联系在一起， 将定期向受训人员提供指导和反馈。研究的“原材料”将是 作为丰富的正在进行的临床和翻译研究的一部分而获得的人体样本和数据 哈博维尤医学中心和华盛顿大学的课程。 我们之前的培训计划强调了《美国国立卫生研究院路线图》中的关键举措，重点是 板凳研究。我们认识到，板凳研究对感兴趣的潜在受训者不太有吸引力 追求临床医生-科学家的学术生涯，比过去有更多的培训选择。我们 必须注意到这一现实。重定向我们的计划是必要的，以鼓励有前途和感兴趣的人 外科医生研究创伤和危重疾病的生物学。在过去的10年里，我们的研究和研究 事实上，培训计划更多地侧重于翻译研究和系统生物学，而不是 依靠的是板凳研究。我们还为学员提供了更有条理的教育(我们的大部分 最近的实习生通过公共卫生学院获得了硕士学位，所有人都报名参加了 分子生物学、统计学和流行病学的研究生课程。 通过这项申请，并在未来5年内，我们将每年为一名学员提供 翻译研究方法的高级培训和华盛顿大学学院的招生 公共卫生的硕士课程。我们将：(1)通过结对，教育我们的研究员先进的研究方法 他们拥有积极的研究导师、项目和他们选择的资源。(2)提升他们的经验和 有机会获得研究和职业导师的职业成功的可能性。(3)提供额外的教育 与转化型健康科学研究所合作的机会。(四)努力建立真正意义上的 多元化的研究培训企业，将缩小生物医学研究的差距，并带来 为我们的领域带来多样性。 总而言之，我们的研究培训计划的三个部分是：(1)我们的个人研究计划 我们的积累经验为以下方面提供了原材料和直接经验(2)扩大机会 为了获得硕士学位而进行的高级课程工作(3)支持 生物医学研究教育，在负责任的研究行为和环境方面进行强有力的培训 鼓励合作。

Project Summary/Abstract The focus of this proposed new post-doctoral training program is to educate clinician-scientists, primarily surgeons and surgical trainees, in the techniques and methods that comprise the fields of translational research and systems biology. Each trainee will be linked with a research mentor and a career mentor who will provide guidance and feedback on a regular basis to the trainee. The research “raw material” will be human samples and data that are obtained as part of the rich ongoing clinical and translational research programs at Harborview Medical Center and the University of Washington. Our previous training program emphasized “Key Initiatives” from the “NIH Roadmap” with a focus on bench research. We recognize that bench research is less appealing to potential trainees who are interested in pursuing an academic career as clinician-scientists and have more options for training than in the past. We must be attentive to this reality. Redirecting our program is necessary to encourage promising and interested surgeons to study the biology of trauma and critical illness. Over the past 10 years our research and research training programs have de facto become more focused on translational research and systems biology and less reliant on bench research. We have also provided our trainees with more structured education (most of our recent trainees have obtained a Master's degree through the school of public health and all have enrolled in graduate level courses in molecular biology, statistics and epidemiology. With this application and over the next 5 years, we will provide one trainee per year a core curriculum of advanced training in translational research methods and enrollment in the University of Washington's School of Public Health's master's program. We will: (1) Educate our fellows in advanced research methods, by pairing them with active research mentors, programs and resources of their choice. (2) Enhance their experience and likelihood of career success with access to research and career mentors. (3) Offer additional educational opportunities in collaboration with the Institute of Translational Health Sciences. (4) Strive to establish a truly diverse research training enterprise that will reduce disparity in biomedical research and bring the benefits of diversity to our field. In summary the three legs of our research training program are: (1) Our individual research programs and our cumulative experience provide the raw material and direct experience (2) Expanded opportunities for advanced course work in order to obtain a Master's degree (3) An institutional environment that supports biomedical research education with robust training in the responsible conduct of research and an environment encouraging collaboration.