MULTIDISCIPLINARY TRAINING IN PULMONARY RESEARCH

摘要 这个机构的国家研究服务奖旨在培养熟练的调查人员与研究- 以解决肺部疾病的基础，转化和临床问题为导向的职业。的结构 该计划是基于这样的前提，即培训需要1）多学科的方法，2）关闭 学生/博士后和指导团队之间的关系，以及3）具有广度和 在基础，转化和临床科学的深度。在这个肺计划的培训跨越学科， 包括细胞和分子生物学、免疫学、微生物学、毒理学、生物化学、肺和危重病 护理医学、传染病和生殖医学。主要研究主题包括：肺免疫学， 炎症和感染;肺纤维化和重塑;烟草和生物质烟雾和慢性 阻塞性肺病;以及空气污染对健康的影响。4名博士后和4名博士后 每年都将为学员提供支助。对肺部研究感兴趣的博士前学生将被接受， 通过生物医学科学研究生教育（GEBS）计划进行培训， 他们的资格考试博士前培训生将获得长达3年的支持。博士后 参与肺相关研究的受训者也是培训的候选人，并由 这个节目的成员。MD/DO候选人来自成人肺和 重症监护医学、过敏/免疫学/流变学、新生儿学和传染病。只有 顶级候选人将根据潜在的成功和认真的承诺，肺 以研究为导向的职业在培训补助金的当前周期，我们建立并成功地 招募了两名医学博士学员进行新的研究。这条赛道需要4年的亚专业培训， 研究培训和支持在最后2年发生在这个补助金，以及具体的期望 在培训结束前提交出版物和研究补助金。直接的研究经验 导师是培训的主要机制，辅以教学课程、研讨会、会议， 期刊俱乐部，并在研究伦理，人类和动物实验，并授予写作指令。所有 学员有机会获得新的机构范围内的职业发展道路，赠款写作，关键 思考、体验式学习等等。项目学员还将制定研究协议和计划 在导师团队的监督下这项培训计划将有助于满足不同的需求， 在学术界、政府和工业界从事肺生物学和疾病的科学研究。研究和 这些学员的扩展培训将提高我们对呼吸系统如何应对 伤害和环境挑战，并将通过开发新的和改进的途径来改善公共卫生 用于预防和治疗肺部疾病。

Abstract This Institutional National Research Service Award is designed to develop skilled investigators with research- oriented careers directed at solving basic, translational and clinical problems in lung disease. The structure of the program is based on the premise that training requires 1) a multidisciplinary approach, 2) a close relationship between the student/postdoc and mentoring team, and 3) a training environment with breadth and depth in basic, translational and clinical sciences. Training in this Pulmonary program spans disciplines that include cell and molecular biology, immunology, microbiology, toxicology, biochemistry, pulmonary and critical care medicine, infectious diseases and neonatology. Major research themes include: lung immunology, inflammation and infection; pulmonary fibrosis and remodeling; tobacco and biomass smoke and chronic obstructive pulmonary disease; and the health effects of air pollution. Four predoctoral and 4 postdoctoral trainees will be supported each year. Predoctoral students interested in lung research will be accepted for training through the Graduate Education in Biomedical Sciences (GEBS) programs, after they have passed their qualifying examinations. Predoctoral trainees will be supported for up to 3 years. Postdoctoral PhD trainees involved in lung-related research are also candidates for training, and are identified and recruited by members of this program. The MD/DO Candidates come from training programs in adult Pulmonary and Critical Care Medicine, Allergy/Immunology/Rheumatology, Neonatology, and Infectious Diseases. Only the top candidates will be considered based on potential success in and serious commitment to a pulmonary research-oriented career. During the current cycle of the training grant, we established and successfully recruited two MD trainees for a new research track. This track requires 4 years of subspecialty training with research training and support on this grant occurring in the final 2 years, and specific expectations of publications and research grant submission by the end of training. A direct research experience with research mentors forms the primary mechanism for training, supplemented by didactic courses, seminars, conferences, journal clubs, and instruction in research ethics, human and animal experimentation, and grant writing. All trainees have access to new Institution-wide programs in career development paths, grant writing, critical thinking, experiential learning and more. Program trainees will also develop research protocols and plans under the supervision of their mentoring team. This training program will help to meet the diverse need for scientific investigators in lung biology and disease in Academia, Government, and Industry. Research and expanded training by these trainees will enhance our understanding of how the respiratory system responds to injury and environmental challenges, and will improve public health by developing new and improved avenues for the prevention and treatment of lung disease.