Learning Health System training program: PROgRESS--Patient/ pRactice Outcomes and Research in Effectiveness and Systems Science

项目总结 在相关临床证据的生成、广泛实施经过验证的临床证据方面存在重大差距 对实践的干预，以及制定知情政策。设计了学习型医疗保健系统 为了“为每个患者和提供者的协作医疗选择生成和应用最佳证据， 推动发现过程作为患者护理的自然结果，并确保创新、质量、安全、 以及医疗保健方面的价值。 范德比尔特致力于培养一支受过正式培训并精通Best的调查人员队伍 整合科学发现、证据实施、信息和评估的方法 学习型医疗系统中的健康政策。我们建议确定范德比尔特患者， 有效性和系统科学(进展)计划的实践成果和研究 交叉培训博士后研究人员，重点是三个核心学科的学习医疗系统： 1)以患者为中心的结果研究--确定哪些策略对患者最有效；2) 实施科学--将这些有效的战略付诸实践并进行评估；以及，3)健康 政策/社区健康-影响政策，使所有患者受益，并改善社区健康。 通过交叉培训这些领域的研究人员，我们将把不同领域的受训者和导师聚集在一起。 学科和模范团队科学；我们将提供榜样和论坛，展示智力 跨学科研究在促进人类健康方面的生产力和实际效益；我们将 支持团队填补知识空白并将知识转化为应用的方法。一个多样化的 通过临床/研究奖学金，一门蓬勃发展的实施科学，可以获得一批有才华的申请者 计划，一个定位良好的卫生政策系，以及包括梅哈里医学院在内的合作伙伴。 进步实习生将有机会获得可靠的教师导师，得到持续的联邦资金和 指导早期职业实习生的广泛记录。每位学员的奖学金监督委员会 (SOC)将在以患者为中心的结果研究中从经验丰富的导师池中挑选， 实施科学与卫生政策/社区卫生。该计划将包括3个培训部分 授课2年以上：1)高级教学，包括学位课程或重点课堂作业；2)正规教学 导师制，为学员准备学习卫生系统科学的K级培训；以及3)体验式 通过开展研究项目进行学习。学员将得到一系列机构的支持 用于培训和发展的资源，包括：正在进行的卫生服务工作；临床质量和 实施研究学术系列、期刊俱乐部、生物统计学研讨会、临床和翻译 研讨会和同伴辅导活动。综上所述，这些资源为 培养下一代学习卫生系统研究人员。

PROJECT SUMMARY Major gaps exist in the generation of relevant clinical evidence, widespread implementation of proven clinical interventions into practice, and formulation of informed policies. The learning healthcare system is designed to “generate and apply the best evidence for the collaborative healthcare choices of each patient and provider, drive the process of discovery as a natural outgrowth of patient care, and ensure innovation, quality, safety, and value in healthcare.” Vanderbilt is committed to develop a cadre of investigators who are formally trained and well versed in best methods for integrating scientific discovery, evidence implementation, and information and evaluation of health policies within the learning healthcare system. We propose to establish the Vanderbilt Patient, pRactice Outcomes and Research in Effectiveness and Systems Science (PROgRESS) Program to cross train post-doctoral investigators with the focus of the learning healthcare system in three core disciplines: 1) Patient Centered Outcomes Research -To determine which strategies are most effective for patients; 2) Implementation Science-To implement and evaluate those effective strategies into practice; and, 3) Health Policy/ Community Health-To influence policy to benefit all patients and improve health of the community. By cross training researchers in these areas we will draw together groups of trainees and mentors across disciplines and model team science; we will provide role models and forums that demonstrate the intellectual productivity and practical benefits of interdisciplinary research in advancing human health; and we will endorse team approaches to filling gaps in knowledge and translating knowledge into application. A diverse pool of talented applicants is available through clinical/research fellowships, a thriving Implementation Science program, a well-positioned Department of Health Policy, and in partners including Meharry Medical College. PROgRESS trainees will have access to well-established faculty mentors with sustained federal funding and an extensive track record of mentoring early career trainees. Each trainee's Scholarship Oversight Committee (SOC) will draw from an experienced pool of mentors in Patient Centered Outcomes Research, Implementation Science and Health Policy/Community Health. The program will have 3 training components conducted over 2 years: 1) advanced didactics, including degree program or focused classwork; 2) formal mentorship that prepares trainees for K level training in Learning Health Systems science; and 3) experiential learning through the conduct of a research project. Trainees will be supported by a broad array of institutional resources for training and development, including: Health Services Works in Progress; Clinical Quality and Implementation Research scholarly series, journal clubs, Biostatistics Seminars, clinical and translational seminars, and peer-mentoring activities. Taken together, these resources provide an optimal environment for developing the next generation of Learning Health System researchers.